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CATH Superfamily 3.40.718.10

Isopropylmalate Dehydrogenase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Isopropylmalate Dehydrogenase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2
Isocitrate dehydrogenase [NADP]
715
3D
 6bl2C00 - 83.1
1
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
619
3D
 3blxO00 - 90.9
3
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
554
3D
 3blxP00 - 84.4
4
3-isopropylmalate dehydrogenase
517
3D
 3vmlA00 - 83.1
5
Isocitrate dehydrogenase [NADP]
459
3D
 9icdA00 - 60.0
6
3-isopropylmalate dehydrogenase
404
3D
 4wuoB00 - 95.2
7
Isocitrate dehydrogenase [NADP]
223 - - 64.1
8
Phosphate acyltransferase
204 - - 57.6
9
Isocitrate dehydrogenase [NAD] regulatory subunit 1
189 - - 64.7
10
4-hydroxythreonine-4-phosphate dehydrogenase
188
3D
 1ptmB00 - 41.7
11
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
154
3D
 5yvtB00 - 63.9
12
Homoisocitrate dehydrogenase, mitochondrial
122
3D
 3ty4B00 - 71.4
13
Tartrate dehydrogenase
89 - - 9.2
14
Isocitrate dehydrogenase
NAD(+
59 - - 91.0
15
Phosphate butyryltransferase
54 - - 45.2
16
Isocitrate dehydrogenase [NADP]
50 - - 73.3
19
Homoisocitrate dehydrogenase
44
3D
 3asjD00 - 88.4
17
Isocitrate dehydrogenase [NADP]
34
3D
 1zorB00 - 42.3
18
Isocitrate dehydrogenase [NADP]
33
3D
 4hcxB00 - 41.0
28
3-isopropylmalate dehydrogenase
30
3D
 5hn6A00 - 82.7
20
Isocitrate dehydrogenase
29 - - 60.9
21
Isocitrate dehydrogenase 3
NAD(+
21 - - 27.3
22
Isocitrate dehydrogenase
NADP(+
20 - - 32.2
26
3-isopropylmalate dehydrogenase
20
3D
 2g4oD00 - 10.1
23
Isocitrate dehydrogenase [NADP]
19 - - 2.5
29
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
16
3D
 5yvtA00 - 42.1
24
Isocitrate dehydrogenase
NADP(+
16 - - 49.4
25
Isocitrate dehydrogenase [NADP]
14 - - 18.8
27
Probable LYS12-Homo-isocitrate dehydrogenase
11 - - 19.2
30
Isocitrate dehydrogenase [NADP]
9 - - 9.7
33
Isocitrate dehydrogenase [NADP]
5 - - 10.6
32
GM20069
5 - - 11.2
31
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
5 - - 14.0
34
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
5 - - 5.3
35
Isocitrate dehydrogenase 3
NAD+
4 - - 17.9
36
3-isopropylmalate dehydrogenase
4 - - 7.2
38
1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase
4 - - 3.7
37
CG3483 protein
4 - - 4.6
39
NADP-dependent isocitrate dehydrogenase, putative
3 - - 29.5
42
Uncharacterized protein
3 - - 0.0
40
Uncharacterized protein
3 - - 12.7
41
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
3 - - 6.3
43
3-isopropylmalate dehydrogenase
LeuB
2 - - 34.5
51
Isocitrate dehydrogenase, putative
2 - - 27.6
48
Isocitrate dehydrogenase [NAD] regulatory subunit 3 mitochondrial
2 - - 0.0
53
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
2 - - 43.2
46
Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
2 - - 0.0
44
Peroxisomal isocitrate dehydrogenase [NADP]
2 - - 42.6
49
Isocitrate dehydrogenase 3
NAD+
2 - - 10.4
45
NAD
H
2 - - 0.0
50
Isocitrate dehydrogenase [NADP]
2 - - 2.9
47
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
2 - - 0.0
52
Isocitrate dehydrogenase 3
NAD+
2 - - 40.7
54
Isocitrate dehydrogenase 3
NAD+
2 - - 45.5
71
Isocitrate dehydrogenase [NADP]
1 - - 0.0
58
Putative isocitrate dehydrogenase [NAD] subunit-like 4
1 - - 0.0
61
Isocitrate dehydrogenase
1 - - 0.0
55
Uncharacterized protein
1 - - 0.0
57
Isocitrate dehydrogenase 3
NAD+
1 - - 0.0
74
Isopropylmalate dehydrogenase1
1 - - 0.0
68
Isocitrate dehydrogenase [NADP]
1 - - 0.0
66
Isocitrate dehydrogenase [NADP]
1 - - 0.0
59
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
1 - - 0.0
62
Isocitrate dehydrogenase, putative
1 - - 0.0
64
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
1 - - 0.0
60
Uncharacterized protein
1 - - 0.0
69
Isocitrate dehydrogenase [NADP]
1 - - 0.0
72
Uncharacterized protein
1 - - 0.0
73
Pentatricopeptide repeat-containing protein
1 - - 0.0
67
Isocitrate dehydrogenase [NADP]
1 - - 0.0
65
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
1 - - 0.0
63
Isocitrate/isopropylmalate dehydrogenase family protein
1 - - 0.0
56
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
1 - - 0.0
70
Uncharacterized protein
1 - - 0.0
75
Isopropylmalate dehydrogenase1
1 - - 0.0