The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
BRCT domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
414
3D
2k7fA00 - 96.8
2
298
3D
2ep8A01 - 92.9
6
248
3D
4y2gA01 - 93.7
3
234
3D
5ecgD01 - 90.7
5
211
3D
5ecgD02 - 92.4
4
205 - - 70.3
7
177 - - 85.4
8
174
3D
2d8mA01 - 93.0
10
168
3D
3olcX03 - 98.9
9
163
3D
2ebwA00 - 81.6
12
161
3D
3qvgD00 - 93.0
11
160
3D
4id3B00 - 98.0
25
154
3D
4y2gA02 - 92.8
13
147
3D
3fa2B02 - 51.1
15
141
3D
4n40A03 - 44.8
14
139 - - 91.5
16
135
3D
4n40A02 - 51.9
17
133
3D
3sqdB02 - 43.1
19
130
3D
3fa2B01 - 68.0
20
128
3D
3olcX02 - 95.2
18
128
3D
3al3A01 - 96.6
21
127
3D
3ueoD02 - 96.7
23
114
3D
3pd7B00 - 96.3
22
113
3D
1wf6A01 - 94.8
24
106 - - 78.5
29
102
3D
3ueoD01 - 99.3
26
101 - - 73.8
27
96
3D
3ii6Y01 - 94.7
28
95
3D
3al3A02 - 91.8
32
94
3D
3qvgC00 - 88.7
33
91
3D
3olcX01 - 89.4
30
89
3D
2cokA00 - 87.1
31
88
3D
2jw5A00 - 97.8
35
84
3D
2htfA00 - 95.8
34
83 - - 25.7
36
81
3D
3sqdB01 - 34.7
37
80
3D
3k05B02 - 45.2
40
69
3D
2etxB01 - 42.2
47
68
3D
3u3zA01 - 73.6
38
67 - - 39.8
41
66
3D
2coeA01 - 82.5
39
65 - - 71.5
42
62 - - 43.7
43
57 - - 36.0
44
55 - - 99.4
45
54 - - 81.3
46
52 - - 90.1
53
51
3D
3u3zA02 - 71.1
49
51
3D
4xq0A03 - 88.9
48
50 - - 84.7
50
48
3D
3ii6Y03 - 74.3
51
45 - - 96.0
55
41
3D
3pa6C00 - 53.0
52
37 - - 86.5
54
34 - - 90.3
56
29 - - 63.3
57
29 - - 90.8
58
28 - - 38.8
59
27 - - 72.2
60
25 - - 82.3
62
25 - - 5.1
61
25 - - 81.2
63
25 - - 56.1
65
23 - - 75.9
64
23 - - 76.2
66
Eurofung
22 - - 81.3
67
21 - - 75.0
80
20
3D
6hm3A02 - 89.9
69
20 - - 68.6
68
20 - - 7.4
70
20 - - 46.5
71
19 - - 7.6
72
19 - - 71.6
91
19
3D
3t7kB02 - 73.2
74
18 - - 81.4
77
18 - - 92.2
75
18 - - 92.6
73
18 - - 54.0
89
17
3D
3oq4E00 - 47.1
76
17 - - 0.0
83
Rad9
17
3D
2vxbB01 - 87.2
78
16 - - 31.6
79
16 - - 14.7
82
15 - - 41.2
81
15 - - 89.5
84
14 - - 78.1
85
14 - - 10.8
87
14 - - 15.3
86
14 - - 74.1
90
13 - - 55.6
93
13
3D
2l42A00 - 24.4
88
Chs5
13 - - 59.5
92
12 - - 44.7
99
11 - - 1.4
96
11 - - 7.5
94
11 - - 76.6
98
11 - - 18.5
100
11 - - 16.0
101
11 - - 14.7
95
11 - - 13.9
97
11 - - 39.0
105
10
3D
1z56C01 - 0.9
103
10 - - 4.5
102
10 - - 44.5
112
9 - - 2.3
110
9 - - 5.2
109
9 - - 0.9
107
9 - - 9.2
111
9 - - 0.0
113
9 - - 33.4
108
9 - - 78.5
106
9 - - 43.9
104
9 - - 1.2
119
BRCT
8 - - 35.5
117
8 - - 41.3
115
8 - - 63.2
118
8 - - 83.7
116
8 - - 37.6
114
8 - - 43.8
124
7 - - 92.7
121
7 - - 10.3
123
7 - - 13.7
125
7 - - 87.1
120
7 - - 31.2
122
7 - - 3.9
129
6 - - 38.2
131
6 - - 7.8
126
6 - - 5.8
133
6 - - 4.4
135
6 - - 33.3
130
6 - - 19.3
128
6 - - 11.8
132
6 - - 7.8
134
6 - - 6.3
127
6 - - 13.7
141
5 - - 6.2
143
5 - - 20.8
137
5 - - 10.9
145
5 - - 10.1
140
5 - - 24.5
142
5 - - 0.0
139
5 - - 2.5
144
5 - - 25.6
136
5 - - 13.1
317
5
3D
2vxcB02 - 0.0
146
Eurofung
5 - - 81.5
138
5 - - 19.7
170
4 - - 31.5
165
4 - - 6.8
168
BRCT
4 - - 12.6
148
4 - - 5.9
157
4 - - 2.7
163
4 - - 1.9
307
4
3D
3hufC02 - 0.0
154
4 - - 9.3
147
4 - - 6.2
152
4 - - 83.9
160
4 - - 7.9
167
4 - - 87.1
150
4 - - 6.0
159
4 - - 0.0
162
4 - - 3.5
169
4 - - 30.4
172
4 - - 27.2
350
4
3D
3l41A01 - 0.0
158
4 - - 11.1
149
4 - - 7.5
156
4 - - 16.8
171
4 - - 88.1
166
4 - - 7.1
153
4 - - 1.3
349
4
3D
3l41A02 - 0.0
155
4 - - 6.5
161
4 - - 0.0
164
4 - - 7.6
151
4 - - 67.6
173
4 - - 74.7
184
3 - - 8.7
181
3 - - 21.5
192
3 - - 29.1
179
3 - - 61.5
193
3 - - 45.1
186
3 - - 7.7
176
3 - - 0.0
180
3 - - 66.3
187
3 - - 2.2
175
3 - - 0.0
189
3 - - 5.9
182
3 - - 4.3
197
3 - - 31.2
190
3 - - 59.7
191
3 - - 0.0
178
3 - - 36.0
183
3 - - 1.4
177
3 - - 0.0
196
3 - - 30.3
194
3 - - 44.1
185
3 - - 2.6
198
3 - - 37.8
195
3 - - 77.7
174
3 - - 1.1
188
3 - - 4.4
232
2 - - 0.0
207
2 - - 0.0
281
2 - - 38.8
252
2 - - 0.0
224
2 - - 0.0
279
2 - - 0.0
263
2 - - 0.0
199
2 - - 22.2
273
2 - - 7.2
258
2 - - 0.0
248
2 - - 0.0
234
Mammalian Rho GEF
2 - - 0.0
205
2 - - 26.7
264
2 - - 0.0
283
2 - - 51.0
226
2 - - 0.0
237
2 - - 0.0
256
Pax-2, IA-1/6, Smad-2 interacting protein
2 - - 0.0
215
2 - - 12.4
270
2 - - 0.0
343
2
3D
4bmdA01 - 0.0
261
2 - - 0.0
212
2 - - 19.4
257
Pax-2, IA-1/6, Smad-2 interacting protein
2 - - 0.0
202
2 - - 3.4
247
2 - - 8.2
242
2 - - 5.2
254
2 - - 0.0
200
2 - - 0.0
228
2 - - 0.0
211
2 - - 10.1
218
2 - - 10.0
221
2 - - 0.0
274
2 - - 4.4
250
2 - - 0.0
276
2 - - 2.0
240
2 - - 10.0
230
2 - - 2.0
239
2 - - 0.0
269
2 - - 0.0
206
2 - - 8.9
245
2 - - 37.1
266
2 - - 1.4
223
2 - - 0.0
216
2 - - 11.0
272
2 - - 3.4
262
2 - - 1.8
225
2 - - 0.0
278
2 - - 0.0
222
2 - - 0.0
217
2 - - 1.1
209
2 - - 0.0
267
2 - - 12.9
233
2 - - 0.0
280
2 - - 1.2
204
2 - - 0.0
253
2 - - 0.0
236
2 - - 0.0
260
2 - - 0.0
227
2 - - 0.0
259
2 - - 0.0
249
2 - - 42.0
214
2 - - 34.8
244
2 - - 0.0
235
Mammalian Rho GEF
2 - - 0.0
265
2 - - 0.0
282
2 - - 40.0
246
2 - - 3.7
229
Eurofung
2 - - 0.0
210
2 - - 0.0
271
2 - - 0.0
342
2
3D
4bmdA02 - 0.0
213
2 - - 27.9
243
2 - - 8.6
203
2 - - 44.3
268
2 - - 6.7
238
2 - - 0.0
255
Pax-2, IA-1/6, Smad-2 interacting protein
2 - - 0.0
219
2 - - 3.5
220
2 - - 0.0
275
2 - - 48.8
251
Pax-2, IA-1/6, Smad-2 interacting protein
2 - - 0.0
208
2 - - 0.0
241
2 - - 3.9
201
2 - - 0.0
231
2 - - 0.0
277
2 - - 0.0
294
1 - - 0.0
326
1 - - 0.0
305
1 - - 0.0
319
1 - - 0.0
336
1 - - 0.0
365
Eurofung
1 - - 0.0
351
1 - - 0.0
310
Nbs
1 - - 0.0
334
1 - - 0.0
345
1 - - 0.0
288
1 - - 0.0
320
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
297
1 - - 0.0
300
1 - - 0.0
285
1 - - 0.0
366
1 - - 0.0
323
1 - - 0.0
361
1 - - 0.0
299
1 - - 0.0
289
1 - - 0.0
290
1 - - 0.0
341
1 - - 0.0
309
1 - - 0.0
354
1 - - 0.0
316
1 - - 0.0
314
1 - - 0.0
302
1 - - 0.0
356
1 - - 0.0
325
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
363
1 - - 0.0
331
1 - - 0.0
358
1 - - 0.0
348
1 - - 0.0
312
1 - - 0.0
370
1 - - 0.0
368
1 - - 0.0
327
1 - - 0.0
304
1 - - 0.0
311
1 - - 0.0
359
1 - - 0.0
335
1 - - 0.0
344
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
293
1 - - 0.0
362
1 - - 0.0
318
1 - - 0.0
337
1 - - 0.0
364
1 - - 0.0
295
1 - - 0.0
296
1 - - 0.0
352
1 - - 0.0
321
1 - - 0.0
306
1 - - 0.0
340
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
330
1 - - 0.0
360
1 - - 0.0
353
1 - - 0.0
315
1 - - 0.0
284
1 - - 0.0
367
1 - - 0.0
322
1 - - 0.0
355
1 - - 0.0
298
1 - - 0.0
339
1 - - 0.0
303
1 - - 0.0
347
1 - - 0.0
313
1 - - 0.0
357
1 - - 0.0
324
1 - - 0.0
286
1 - - 0.0
369
1 - - 0.0
332
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
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