CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.10190 | BRCT domain |
Domain Context
CATH Clusters
Superfamily | BRCT domain |
Functional Family | DNA-directed DNA/RNA polymerase mu |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q9NP87
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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UniProtKB Entries (1)
Q9NP87 |
DPOLM_HUMAN
Homo sapiens
DNA-directed DNA/RNA polymerase mu
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PDB Structure
PDB | 2HTF |
External Links | |
Method | SOLUTION NMR |
Organism | Escherichia |
Primary Citation |
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.
Biochemistry
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