CATH Classification

Domain Context

CATH Clusters

Superfamily BRCT domain
Functional Family DNA polymerase

Enzyme Information

4.2.99.-
Other carbon-oxygen lyases.
based on mapping to UniProt Q9UGP5
2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UGP5
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9UGP5
DPOLL_HUMAN
Homo sapiens
DNA polymerase lambda

PDB Structure

PDB 2JW5
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Polymerase Lambda BRCT domain
Mueller, G.A., Moon, A.F., DeRose, E.F., Davis, B.J., Ramsden, D.A., Pedersen, L.C., London, R.E.
To be Published
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