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CATH Superfamily 1.10.150.80

HRDC domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HRDC domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Putative exosome component 10
372
3D
 3sahB02 - 97.4
2
ATP-dependent DNA helicase RecQ
249
3D
 1wudD00 - 94.9
3
Bloom syndrome RecQ-like helicase
130
3D
 4o3mA04 - 89.1
4
ATP-dependent DNA helicase RecQ
116 - - 57.3
5
Werner syndrome ATP-dependent helicase homolog
94
3D
 2e1fA01 - 93.8
6
Ribonuclease D
60
3D
 1yt3A02 - 22.6
7
Ribonuclease D
49
3D
 1yt3A03 - 48.1
8
Polynucleotidyl transferase ribonuclease H fold protein with HRDC domain
35 - - 84.4
9
3'-5' exonuclease
30 - - 6.2
10
ATP-dependent DNA helicase Q-like 4A
21 - - 73.5
11
ATP-dependent DNA helicase
18 - - 68.3
12
Exosome complex exonuclease RRP6
16 - - 4.5
14
ATP-dependent DNA helicase RecQ
15 - - 7.5
13
Bloom syndrome protein homolog
15 - - 80.6
15
Putative ribonuclease D
15 - - 47.0
16
ATP-dependent DNA helicase
13 - - 77.5
19
ATP-dependent DNA helicase
12 - - 92.7
18
Putative ribonuclease D
12 - - 47.0
22
Exosome complex exonuclease RRP6
12
3D
 5c0yB02 - 1.3
17
ATP-dependent DNA helicase RecQ
12 - - 0.0
20
RecQ family helicase MusN
11 - - 79.1
21
ATP-dependent DNA helicase RecQ
11
3D
 2rhfA00 - 76.1
27
ATP-dependent helicase SGS1
9
3D
 1d8bA00 - 10.5
23
Unplaced genomic scaffold supercont1.38, whole genome shotgun sequence
9 - - 19.9
25
HRDC domain./PIF1 helicase
9 - - 11.4
24
Unplaced genomic scaffold supercont1.37, whole genome shotgun sequence
9 - - 13.4
29
ATP-dependent DNA helicase RecQ
8 - - 3.0
26
ATP-dependent DEAD/H DNA helicase recQ, putative
8 - - 45.1
28
ATP-dependent DNA helicase RecQ
8 - - 17.9
31
Ribonuclease D
7 - - 2.5
33
ATP-dependent DNA helicase RecQ
7 - - 0.0
30
Ribonuclease D
7 - - 1.6
32
Exosome complex exonuclease RRP6, putative
7 - - 2.8
34
ATP-dependent helicase SGS1, putative
6 - - 7.6
35
ATP-dependent DNA helicase RecQ
5 - - 75.5
36
ATP-dependent DNA helicase, RecQ family protein
4 - - 94.1
37
ATP-dependent DNA helicase
3 - - 11.4
38
Ribonuclease D
3 - - 14.6
39
ATP-dependent DNA helicase RecQ family protein
2 - - 40.0
40
RecQ
2 - - 45.1
41
ATP-dependent DNA helicase
2 - - 1.4
43
Uncharacterized protein
2 - - 20.9
44
Uncharacterized protein
2 - - 13.4
42
ATP-dependent DNA helicase RecQ
2 - - 8.0
45
Predicted protein
2 - - 1.1
48
ATP-dependent DNA helicase
1 - - 0.0
55
Uncharacterized protein
1 - - 0.0
49
ATP-dependent DNA helicase
1 - - 0.0
50
Ribonuclease D, putative
1 - - 0.0
51
Ribonuclease D, putative
1 - - 0.0
46
ATP-dependent DNA helicase hus2/rqh1
1 - - 0.0
52
Uncharacterized protein
1 - - 0.0
53
Uncharacterized protein
1 - - 0.0
47
AFL159Wp
1 - - 0.0
54
Uncharacterized protein
1 - - 0.0