CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.150 | DNA polymerase; domain 1 | |
1.10.150.80 | HRDC domain |
Domain Context
CATH Clusters
Superfamily | HRDC domain |
Functional Family | Ribonuclease D |
Enzyme Information
3.1.13.5 |
Ribonuclease D.
based on mapping to UniProt P09155
Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
-!- Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect. -!- tRNA terminating with a 3'-phosphate is completely inactive. -!- This enzyme can convert a tRNA precursor into a mature tRNA.
|
UniProtKB Entries (1)
P09155 |
RND_ECOLI
Escherichia coli K-12
Ribonuclease D
|
PDB Structure
PDB | 1YT3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal Structure of Escherichia coli RNase D, an Exoribonuclease Involved in Structured RNA Processing
Structure
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