CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.80 | HRDC domain |
Domain Context
CATH Clusters
| Superfamily | HRDC domain |
| Functional Family | Ribonuclease D |
Enzyme Information
| 3.1.13.5 |
Ribonuclease D.
based on mapping to UniProt P09155
Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
-!- Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect. -!- tRNA terminating with a 3'-phosphate is completely inactive. -!- This enzyme can convert a tRNA precursor into a mature tRNA.
|
UniProtKB Entries (1)
| P09155 |
RND_ECOLI
Escherichia coli K-12
Ribonuclease D
|
PDB Structure
| PDB | 1YT3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Escherichia coli RNase D, an Exoribonuclease Involved in Structured RNA Processing
Structure
|