CATH Superfamily 6.10.140.2220
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Protein kinase C-binding protein 1 isoform C
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 19 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | A8C4G9 (/IPI) Q20741 (/IPI) Q9ULU4 (/IPI) |
|
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
2 | A0A0G2K9F7 (/IPI) A8C4G9 (/IPI) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
1 | D5LMF5 (/IDA) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
1 | Q9ULU4 (/IMP) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
1 | Q9ULU4 (/ISS) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q20741 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q9ULU4 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q7KRS9 (/ISM) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | Q9ULU4 (/IDA) |
|
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.
|
1 | Q9ULU4 (/IDA) |
|
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
|
1 | D5LMF5 (/IPI) |
|
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
|
1 | Q9ULU4 (/ISS) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
1 | Q9ULU4 (/IDA) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Modulation of excitatory postsynaptic potential GO:0098815
Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Regulation of postsynaptic density protein 95 clustering GO:1902897
Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Positive regulation of dendritic spine maintenance GO:1902952
Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
2 | A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) |
|
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
2 | A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) |
|
Modulation of excitatory postsynaptic potential GO:0098815
Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
2 | A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) |
|
Regulation of postsynaptic density protein 95 clustering GO:1902897
Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.
|
2 | A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) |
|
Positive regulation of dendritic spine maintenance GO:1902952
Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.
|
2 | A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
1 | P87311 (/ISO) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | D5LMF5 (/IMP) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | Q20741 (/IMP) |
|
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q9ULU4 (/IMP) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q20741 (/IGI) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
|
12 |
A2A482 (/ISO)
A2A483 (/ISO)
A2A484 (/ISO)
A2A485 (/ISO)
E9Q8D1 (/ISO)
Q3U1M7 (/ISO)
Q3UH28 (/ISO)
Q3V1I9 (/ISO)
Q3V437 (/ISO)
Q80XT8 (/ISO)
(2 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) D5LMF5 (/IDA) Q9ULU4 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) |
|
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
2 | A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) |
|
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
|
2 | A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P87311 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9ULU4 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9ULU4 (/IMP) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P87311 (/HDA) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q20741 (/IDA) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q20741 (/IDA) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P87311 (/HDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | P87311 (/HDA) |
|
MUB1-RAD6-UBR2 ubiquitin ligase complex GO:1990304
A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.
|
1 | P87311 (/ISO) |
