The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: NAD(P)H dehydrogenase (Quinone) FQR1-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 P25349 (/IPI) P25349 (/IPI) P25349 (/IPI) P25349 (/IPI) P25349 (/IPI) P25349 (/IPI) P30821 (/IPI) Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI)
(4 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
7 Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI) Q12335 (/IPI)
NAD(P)H dehydrogenase (quinone) activity GO:0003955
Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
5 C1I202 (/IDA) C1I202 (/IDA) C1I202 (/IDA) Q9LSQ5 (/IDA) Q9LSQ5 (/IDA)
2-hydroxy-1,4-benzoquinone reductase activity GO:0050625
Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).
3 A3F7Q2 (/IDA) A3F7Q2 (/IDA) A3F7Q3 (/IDA)
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2 F4K0D0 (/IDA) Q9I509 (/IDA)
2-hydroxy-1,4-benzoquinone reductase activity GO:0050625
Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).
2 Q59Y37 (/NAS) Q59Y37 (/NAS)
NAD(P)H dehydrogenase (quinone) activity GO:0003955
Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
1 Q9I509 (/IMP)
NAD(P)H dehydrogenase (quinone) activity GO:0003955
Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
1 P30821 (/ISM)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
1 F4K0D0 (/IDA)
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
1 A0A1D8PHR5 (/NAS)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tryptophan metabolic process GO:0006568
The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
7 Q9KQ38 (/ISS) Q9KQ38 (/ISS) Q9KQ38 (/ISS) Q9KQ38 (/ISS) Q9KQ38 (/ISS) Q9KQ38 (/ISS) Q9KQ38 (/ISS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
6 A0A1D8PHR5 (/IGI) A0A1D8PT02 (/IGI) A0A1D8PT02 (/IGI) A0A1D8PT03 (/IGI) Q59Y37 (/IGI) Q59Y37 (/IGI)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
6 A0A1D8PHR5 (/IGI) A0A1D8PT02 (/IGI) A0A1D8PT02 (/IGI) A0A1D8PT03 (/IGI) Q59Y37 (/IGI) Q59Y37 (/IGI)
Aromatic compound catabolic process GO:0019439
The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
3 C1I202 (/IDA) C1I202 (/IDA) C1I202 (/IDA)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
3 F4K0D0 (/IDA) Q9LSQ5 (/IDA) Q9LSQ5 (/IDA)
Seed trichome initiation GO:0090377
The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.
3 A3F7Q2 (/IEP) A3F7Q2 (/IEP) A3F7Q3 (/IEP)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
3 A3F7Q2 (/IEP) A3F7Q2 (/IEP) A3F7Q3 (/IEP)
Secondary cell wall biogenesis involved in seed trichome differentiation GO:0090379
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
3 A3F7Q2 (/IEP) A3F7Q2 (/IEP) A3F7Q3 (/IEP)
Cellular response to auxin stimulus GO:0071365
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
2 Q9LSQ5 (/IDA) Q9LSQ5 (/IDA)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 F4K0D0 (/IEP)
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
1 P30821 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q9I509 (/IMP)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA)
(3 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA) Q12335 (/HDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 A0A1D8PHR5 (/IDA) A0A1D8PT02 (/IDA) A0A1D8PT02 (/IDA) A0A1D8PT03 (/IDA) F4K0D0 (/IDA) O23207 (/IDA) Q59Y37 (/IDA) Q59Y37 (/IDA) Q6NQE2 (/IDA) Q6NQE2 (/IDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P25349 (/IDA) P25349 (/IDA) P25349 (/IDA) P25349 (/IDA) P25349 (/IDA) P25349 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
6 P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA) P25349 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q6FM13 (/IDA) Q6FM13 (/IDA) Q6FXR3 (/IDA) Q6FXR3 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 A3F7Q2 (/TAS) A3F7Q2 (/TAS) A3F7Q3 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 Q5BGN3 (/IDA) Q5BGN3 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q6NQE2 (/IDA) Q6NQE2 (/IDA)
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
2 Q59Y37 (/IDA) Q59Y37 (/IDA)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
2 A0A1D8PT02 (/IDA) A0A1D8PT02 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P30821 (/HDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 F4K0D0 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
1 F4K0D0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P30821 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 F4K0D0 (/IDA)
Mating-type region heterochromatin GO:0031934
Heterochromatic regions of the chromosome found at silenced mating-type loci.
1 P30821 (/IDA)
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