The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Chalcone synthase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747
Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
18 B0FYK7 (/IDA) C0SVZ5 (/IDA) C0SVZ6 (/IDA) C4MBZ5 (/IDA) C4NF90 (/IDA) C4NF91 (/IDA) C6L7V8 (/IDA) C6L7V9 (/IDA) C6L7V9 (/IDA) G4V4T4 (/IDA)
(8 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 O23674 (/IPI) O23674 (/IPI) P13114 (/IPI) P13114 (/IPI) P13114 (/IPI) Q8LDM2 (/IPI) Q8LDM2 (/IPI)
Tetraketide alpha-pyrone synthase activity GO:0090439
Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A .
6 O23674 (/IDA) O23674 (/IDA) Q2U852 (/IDA) Q2U852 (/IDA) Q8LDM2 (/IDA) Q8LDM2 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 B0LDU5 (/ISS) B0LDU6 (/ISS) Q9AU09 (/ISS) Q9AU10 (/ISS) Q9AU11 (/ISS)
Naringenin-chalcone synthase activity GO:0016210
Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.
4 Q2U852 (/ISA) Q2U852 (/ISA) Q53U85 (/ISA) Q53U85 (/ISA)
Naringenin-chalcone synthase activity GO:0016210
Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.
3 P30074 (/IDA) Q8RVK9 (/IDA) Q9FUB7 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q3L7F5 (/IDA) Q58VP7 (/IDA) Q94FV7 (/IDA)
Transferase activity, transferring acyl groups GO:0016746
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
2 L7NCQ3 (/IDA) Q8SAS8 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 C0SVZ5 (/TAS) C0SVZ6 (/TAS)
Tetrahydroxybenzophenone synthase activity GO:0047181
Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.
2 L7NCQ3 (/IDA) Q8SAS8 (/IDA)
Transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747
Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
1 Q939X3 (/IMP)

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chalcone biosynthetic process GO:0009715
The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.
21 P30074 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA) P9WPF1 (/IDA)
(11 more)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
19 P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP)
(9 more)
DIM/DIP cell wall layer assembly GO:0071770
The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
19 P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP)
(9 more)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
16 O23674 (/IDA) O23674 (/IDA) Q2U852 (/IDA) Q2U852 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA)
(6 more)
Flavonoid biosynthetic process GO:0009813
The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
11 C0SVZ5 (/IDA) C0SVZ6 (/IDA) C4MBZ5 (/IDA) C4NF90 (/IDA) C4NF91 (/IDA) C6L7V8 (/IDA) C6L7V9 (/IDA) C6L7V9 (/IDA) Q3L7F5 (/IDA) Q58VP7 (/IDA)
(1 more)
Melanin biosynthetic process GO:0042438
The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
5 B0FYK7 (/IDA) Q54240 (/IDA) Q54240 (/IDA) Q54240 (/IDA) Q9FCA7 (/IDA)
Pollen exine formation GO:0010584
The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.
4 O23674 (/IMP) O23674 (/IMP) Q8LDM2 (/IMP) Q8LDM2 (/IMP)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
4 Q2U852 (/ISA) Q2U852 (/ISA) Q53U85 (/ISA) Q53U85 (/ISA)
Sporopollenin biosynthetic process GO:0080110
The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.
4 O23674 (/IMP) O23674 (/IMP) Q8LDM2 (/IMP) Q8LDM2 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 P13114 (/IEP) P13114 (/IEP) P13114 (/IEP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
3 P13114 (/IEP) P13114 (/IEP) P13114 (/IEP)
Response to gravity GO:0009629
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.
3 P13114 (/IMP) P13114 (/IMP) P13114 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
3 P13114 (/IEP) P13114 (/IEP) P13114 (/IEP)
Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
3 P13114 (/IEP) P13114 (/IEP) P13114 (/IEP)
Flavonoid biosynthetic process GO:0009813
The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
3 P13114 (/IMP) P13114 (/IMP) P13114 (/IMP)
Flavonoid biosynthetic process GO:0009813
The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
3 P13114 (/ISS) P13114 (/ISS) P13114 (/ISS)
Auxin polar transport GO:0009926
The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
3 P13114 (/IMP) P13114 (/IMP) P13114 (/IMP)
Response to UV-B GO:0010224
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
3 P13114 (/IMP) P13114 (/IMP) P13114 (/IMP)
Regulation of anthocyanin biosynthetic process GO:0031540
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
3 P13114 (/IEP) P13114 (/IEP) P13114 (/IEP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q54FI3 (/IGI) Q55E72 (/IGI)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q54FI3 (/IGI) Q55E72 (/IGI)
Sorocarp stalk cell differentiation GO:0031149
The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
2 Q54FI3 (/IGI) Q55E72 (/IGI)
Benzoyl-CoA metabolic process GO:1901787
The chemical reactions and pathways involving benzoyl-CoA.
2 L7NCQ3 (/IDA) Q8SAS8 (/IDA)
Malonyl-CoA metabolic process GO:2001293
The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.
2 L7NCQ3 (/IDA) Q8SAS8 (/IDA)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q55E72 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q55E72 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q55E72 (/IMP)
Resorcinol metabolic process GO:0019505
The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.
1 Q55E72 (/IDA)
Resorcinol metabolic process GO:0019505
The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.
1 Q55E72 (/IMP)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
1 Q55E72 (/IMP)
DIF-1 biosynthetic process GO:0031148
The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
1 Q54FI3 (/IMP)
Sorocarp stalk cell differentiation GO:0031149
The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
1 Q54FI3 (/IMP)
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 Q55E72 (/IMP)
Sorocarp morphogenesis GO:0031288
The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
1 Q54FI3 (/IMP)
Chemotaxis to cAMP GO:0043327
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
1 Q55E72 (/IMP)
Regulation of cAMP-mediated signaling GO:0043949
Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
1 Q55E72 (/IMP)
Sorocarp spore cell differentiation GO:0044671
The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).
1 Q55E72 (/IMP)
Autophagic cell death GO:0048102
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
1 Q54FI3 (/IMP)
Sorocarp sorus development GO:0048837
The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp.
1 Q55E72 (/IMP)
Cannabinoid biosynthetic process GO:1901696
The chemical reactions and pathways resulting in the formation of cannabinoid.
1 Q8RVK9 (/NAS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
19 P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP) P9WPF3 (/IMP)
(9 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA) P9WPF5 (/HDA)
Type III polyketide synthase complex GO:0034083
A polyketide synthase complex that consists of two identical ketosynthase polypeptides.
8 Q2U852 (/IDA) Q2U852 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA) Q4K418 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
7 O23674 (/IDA) O23674 (/IDA) P13114 (/IDA) P13114 (/IDA) P13114 (/IDA) Q8LDM2 (/IDA) Q8LDM2 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P13114 (/IDA) P13114 (/IDA) P13114 (/IDA)
Plant-type vacuole membrane GO:0009705
The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
3 P13114 (/IDA) P13114 (/IDA) P13114 (/IDA)
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
1 Q8RVK9 (/IDA)
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