CATH Superfamily 3.40.30.50
Sep15/SelM thioredoxin-like domain, active-site redox motif
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Sep15/SelM thioredoxin-like domain, active-site redox motif
".
FunFam 1: 15 kDa selenoprotein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O60613 (/IPI) Q923V8 (/IPI) Q9ERR7 (/IPI) Q9VVJ7 (/IPI) |
|
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
|
1 | Q923V8 (/IDA) |
|
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
|
1 | Q9ERR7 (/ISO) |
|
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
|
1 | Q923V8 (/IDA) |
|
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
|
1 | Q9ERR7 (/ISO) |
|
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
|
1 | Q802F3 (/ISS) |
|
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
1 | Q9VVJ7 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
'de novo' posttranslational protein folding GO:0051084
The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.
|
3 | O60613 (/TAS) Q923V8 (/TAS) Q9ERR7 (/TAS) |
|
Selenocysteine metabolic process GO:0016259
The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.
|
1 | Q55FV9 (/IDA) |
|
Sperm chromatin condensation GO:0035092
The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
|
1 | Q923V8 (/IMP) |
|
Sperm chromatin condensation GO:0035092
The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
|
1 | Q9ERR7 (/ISO) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
1 | Q9VVJ7 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
4 | Q6X4M2 (/ISS) Q802F3 (/ISS) Q923V8 (/ISS) Q9ERR7 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9VVJ7 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9VVJ7 (/IDA) |
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
1 | O60613 (/IDA) |
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
1 | Q9ERR7 (/ISO) |
|
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
|
1 | Q9VVJ7 (/HDA) |
