The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Cruciform cutting endonucleaseSC:10CCR4-NOT transcription complex subunit 7CCR4-associated factor 1, putativePoly(A) ribonuclease POP2SC:11Putative phage transposaseGag-Pol polyproteinSC:2Pro-Pol polyproteinSC:3Protein argonaute-2SC:4DNA polymeraseDNA polymeraseDNA polymeraseDNA polymeraseDNA-directed DNA polymeraseDNA polymeraseDNA polymeraseSC:5Interferon-stimulated exonuclease gene 20DNA polymerase IRibonuclease DProtein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2DNA polymeraseSC:6Ribonuclease TDNA polymerase III subunit epsilonExodeoxyribonuclease XERI1 exoribonuclease 3 isoform X13'-5' exoribonuclease 13'-5' exonuclease DinGCell death-related nuclease 4SC:7Exosome component 10Exosome complex exonuclease Rrp6Exosome complex exonuclease RRP6DNA-directed DNA polymeraseSC:8RibonucleaseRibonuclease HIIIRibonuclease HIIRibonuclease HIISC:9Ribonuclease H1Ribonuclease HGag-Pol polyproteinPro-Pol polyproteinCrossover junction endodeoxyribonuclease RuvCOligoribonucleaseRibonuclease HIIRibonuclease HDNA polymerase epsilon catalytic subunitPAN2-PAN3 deadenylation complex catalytic subunit PAN2protein argonaute 10-likePiwi-like RNA-mediated gene silencing 1DNA polymerase epsilon catalytic subunitPOL polyproteinRNA exonuclease NEF-spRNA exonuclease 1 homologepithelial splicing regulatory protein 1 isoform X1DNA polymerase zeta catalytic subunitGag-Pol polyproteinPutative CCR4-associated factor 1 7PAN2-PAN3 deadenylation complex catalytic subunit PAN2IS3, transposase orfBRNA exonuclease 1Retrovirus-related Pol polyprotein from transposon 297-like ProteinExodeoxyribonuclease IPoly(A)-specific ribonuclease PARNepithelial splicing regulatory protein 2 isoform X1IS30-like element IS30 family transposaseTarget of EGR1 protein 1Exonuclease family proteinExonuclease 3'-5' domain containing 2poly(A)-specific ribonuclease PARNDNA polymeraseSporulation inhibitor KapDThree prime repair exonuclease 1Transposon Ty2-DR3 Gag-Pol polyproteinDNA polymerase IWerner syndrome ATP-dependent helicase homologWerner Syndrome-like exonucleaseRNA exonuclease 5 isoform X1CCR4-NOT core complex subunit Caf1IS150, transposase orfBPARN like, ribonuclease domain containing 1PARN like, ribonuclease domain containing 1ERI1 exoribonuclease 2 isoform X1Retrovirus-related Pol polyprotein from transposon 297-like ProteinRNA exonuclease 4Protein RRP6-like 2 isoform ADNA polymerase thetaPutative CCR4-associated factor 1 11Exonuclease domain-containing protein 1Helicase and polymerase-containing protein TEBICHIDNA polymerase nuDNA polymerase-3 subunit epsilonDNA polymerase epsilon catalytic subunit Aexonuclease mut-7 homolog isoform X2Transposase, IS30 familyRBR-type E3 ubiquitin transferaseUncharacterized proteinRibonuclease HIIPolynucleotidyl transferase ribonuclease H fold protein with HRDC domainSmall RNA degrading nuclease 3Exonuclease DPD1 chloroplastic/mitochondrialDNA polymeraseSET domain and mariner transposase fusion geneTn7 transposase BIS1239 transposaseRibonuclease HExonuclease, putativeRibonucleaseRibonuclease HProtein argonaute 33'-5' exonucleaseDNA polymerase III subunit epsilonGag-Pol polyproteinTranscription elongation factor, mitochondrialUncharacterized exonuclease domain-containing protein At3g15140Ribonuclease H1Polynucleotidyl transferase ribonuclease H-like superfamily proteinERI1 exoribonuclease 3 isoform X33'-5' exonuclease/helicase (Wrn), putativeUncharacterized proteinpiRNA biogenesis protein EXD1Werner Syndrome-like exonucleaseUncharacterized proteinFusilli, isoform GDNA helicase, phage-associatedRNA exonuclease 3DNA polymerase III polC-typeIS3-like element IS987 family transposaseDNA polymeraseRibonuclease HIIWerner Syndrome-like exonucleaseRibonuclease HPutative DNA polymerase III epsilon subunit (3'-5' exonuclease)DNA polymerase III polC-typePoly(A)-specific ribonuclease PARN, putativeRibonuclease HPoly(A)-specific ribonuclease PARNDNA polymerase I3'-5' exonucleasePoly(A)-specific ribonuclease PARNPlastid replication-repair enzymeDNA binding protein3'-5' exonuclease domain proteinExoribonuclease, putativePoly(A)-specific ribonuclease PARNExosome complex exonuclease RRP6CAF1 family ribonuclease containing proteinProtein CBG26278CAF1 family ribonuclease, putativeDNA polymerase III PolC-typeDNA polymerasePoly(A)-specific ribonuclease PARNISPsy4, transposaseDNA polymerase IProtein CBG03114Ribonuclease HOligoribonucleaseRibonuclease HEndogenous retrovirus group K member 18 Pol proteinEndogenous retrovirus group K member 6 Pol proteinDNA polymerase IDNA polymerase IPolynucleotidyl transferase, ribonuclease H-like superfamily proteinRibonucleaseDNA polymeraseDNA polymerase III polC-typeBifunctional RNase H/acid phosphataseRBR-type E3 ubiquitin transferaseTransposon Tf2-4 polyproteinDNA polymeraseRibonuclease HRibonuclease, putativeMitochondrial DNA polymerase I protein D, putativeRibonuclease D, putativeExonuclease family proteinRibonuclease HIIExonucleaseSnipper, isoform EPossible transposase3'-5' exoribonucleaseDNA polymerase I-like protein BDNA polymeraseCation-transporting ATPaseRNA exonuclease 5DNA polymerase IRibonuclease, putativeRibonucleaseCAF1 family ribonuclease containing proteinCCR4-NOT transcription complex, subunit 7RNase HYDR514C-like proteinUnplaced genomic scaffold supercont2.5, whole genome shotgun sequenceUncharacterized proteinDNA polymeraseYALI0B06303pUncharacterized proteinEgalitarian, isoform BTransposaseAGO2, isoform ERibonucleaseRibonucleaseChromosome 1, whole genome shotgun sequencePoly(A)-specific ribonuclease PARNCCR4-NOT transcription complex subunit 7Protein RRP6-like 2Putative CCR4-associated factor 1 homolog 11Protein CBG10739Piwi-like protein 1Ribonuclease H1, putativeCAF1 family ribonuclease containing proteinRibonuclease HIIDNA polymerase III epsilon subunitExonuclease, DNA polymerase III, epsilon subunit familyPutative transposaseDNA polymeraseDNA polymeraseUncharacterized proteinPol polyproteinDNA polymerase IDNA polymerase IPolyprotein of viral origin, putativeExosome complex exonuclease RRP6, putativeDNA polymerase epsilon catalytic subunitRNA exonuclease, putativePutative retroelementISDet2, transposase orfB3'-5' exonuclease family proteinPolynucleotidyl transferase, ribonuclease H-like superfamily proteinProbable CCR4-associated factor 1 homolog 5RE72821p1Os07g0112400 proteinExodeoxyribonuclease IERI1 exoribonuclease family member 2ISPsy11, transposase OrfBexonuclease 3'-5' domain-containing protein 2 isoform X5Ribonuclease HIIIDNA polymerase epsilon catalytic subunitDNA polymeraseUncharacterized proteinDNA polymerase IDNA polymerase IProtein piwiDNA polymeraseRetrovirus-related Pol polyprotein from transposon 412-like ProteinUncharacterized proteinYALI0F25729pRibonuclease HRibonuclease HIIUncharacterized proteinExonuclease mut-7RNA exonuclease 4 isoform ACCR4-NOT transcription complex,subunit 7-likeSi:ch1073-296i8.2CCR4-NOT transcription complex subunit 8Exonuclease 3'-5' domain containing 3RibonucleaseTransposon Ty4-P Gag-Pol polyproteinYdc2-catalyt-domain-containing proteinOs01g0566000 proteinIntegrase/recombinase core subunitReverse transcriptase, RNaseH, putativeConserved protein of uncharacterized function, possible transposase remnantOs07g0112200 proteinDNA polymerasePolymerase (DNA directed), thetaDNA polymerase catalytic subunit3'-5' exonuclease, putativeGag-Pol polyproteinDNA polymerase IDNA polymerase I3'-5' exoribonuclease parn-1Putative ribonucleasePutative ribonucleaseUncharacterized proteinDNA polymeraseRibonuclease, putativeCCR4-NOT transcription complex subunit 8DNA polymerase 33'-5' exoribonuclease parn-1Ribonuclease HDNA polymerase IUncharacterized proteinThree prime repair exonuclease, putativeProtein CBG19000Predicted proteinUncharacterized proteinIntegrase/recombinase, core domain family3'-5'_exonuclease_-_putativeGM18382DNA polymerase III subunit epsilonPutative DNA polymerase III, epsilon subunitExonuclease-like proteinDNA polymerase III, epsilon chainProtein CBG02435Ribonuclease HProtein CBG00653Pol polyproteinDNA polymerase IArgonaut-like proteinArgonaute protein wago-1Argonaute (Plant)-Like proteinPoly(A)-specific_ribonuclease_PARN_-_putativeUncharacterized proteinPoly(A)-specific ribonuclease PARNUncharacterized proteinDNA polymeraseDNA polymeraseDNA polymeraseDNA polymerase Pol2Uncharacterized protein C29A10.09cTarget of EGR1, exonucleaseUncharacterized proteinRibonuclease H-like domain-containing proteinProtein CBG03113Uncharacterized proteinPolyproteinPolymerase (DNA directed) nuDNA polymerase IUncharacterized protein3'-5' exonuclease domain-containing protein3'-5' exonuclease eri-1Uncharacterized proteinMitochondrial resolvase Ydc2RibonucleaseGM25386ExonucleaseDNA polymerase III subunit epsilonUncharacterized proteinDNA polymeraseUncharacterized proteinDNA polymerase zeta catalytic subunit, putativePolymerase (DNA directed), thetaAGAP007399-PADNA polymerase IArgonaute-like protein, putativeUncharacterized proteinPoly(A)-specific ribonuclease PARNCAF1 family ribonuclease, putativePolynucleotidyl transferase, ribonuclease H-like superfamily proteinDNA polymeraseUncharacterized proteinDNA polymeraseUncharacterized proteinTransposon Ty3-I Gag-Pol polyproteinUncharacterized proteinPredicted proteinTransposaseUncharacterized proteinUncharacterized proteinChromosome-Segregation and RNAi deficientDNA polymerasePredicted proteinDNA polymerase thetaTarget of EGR1 protein 1Piwi-like protein ergo-1DNA polymeraseDNA polymerase alpha subunit oneAGAP007533-PAPredicted proteinUncharacterized proteinPredicted proteinREV3 like, DNA directed polymerase zeta catalytic subunit
« Back to all FunFams

FunFam 352: Uncharacterized protein

Representative CATH Domain W4YC16/238-412

Sequence alignment 200 sequences

More information on the open source software used on this web site can be found in the Tools page.
CATH-Gene3D is a Global Biodata Core Resource Learn more...