The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: PAN2-PAN3 deadenylation complex catalytic subunit ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P0C581 (/IPI) P0C581 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI)
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
1 Q09798 (/ISM)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
7 P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA)
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
7 P53010 (/IMP) P53010 (/IMP) P53010 (/IMP) P53010 (/IMP) P53010 (/IMP) P53010 (/IMP) P53010 (/IMP)
Postreplication repair GO:0006301
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
7 P53010 (/IGI) P53010 (/IGI) P53010 (/IGI) P53010 (/IGI) P53010 (/IGI) P53010 (/IGI) P53010 (/IGI)
Postreplication repair GO:0006301
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
7 P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI) P53010 (/IPI)
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
1 Q09798 (/ISO)
Protein modification by small protein conjugation or removal GO:0070647
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
1 Q09798 (/IC)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P53010 (/HDA) P53010 (/HDA) P53010 (/HDA) P53010 (/HDA) P53010 (/HDA) P53010 (/HDA) P53010 (/HDA) Q09798 (/HDA)
PAN complex GO:0031251
A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
7 P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA) P53010 (/IDA)
PAN complex GO:0031251
A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
1 Q09798 (/ISO)
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