The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ribonuclease H-like superfamily/Ribonuclease H
".
FunFam 104: Werner Syndrome-like exonuclease
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
12 |
B3LWP6 (/ISS)
B3NZ68 (/ISS)
B4G5C9 (/ISS)
B4I298 (/ISS)
B4JF25 (/ISS)
B4K934 (/ISS)
B4M401 (/ISS)
B4N9D3 (/ISS)
B4PLB3 (/ISS)
B4QUF6 (/ISS)
(2 more) |
|
Single-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008310
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
|
1 | Q9VE86 (/IDA) |
|
Double-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008311
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.
|
1 | Q9VE86 (/IDA) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
1 | Q9VE86 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of mitotic recombination GO:0045950
Any process that inhibits or decreases the rate of DNA recombination during mitosis.
|
11 |
B3LWP6 (/ISS)
B3NZ68 (/ISS)
B4G5C9 (/ISS)
B4I298 (/ISS)
B4JF25 (/ISS)
B4K934 (/ISS)
B4M401 (/ISS)
B4N9D3 (/ISS)
B4PLB3 (/ISS)
B4QUF6 (/ISS)
(1 more) |
|
DNA catabolic process, exonucleolytic GO:0000738
The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
|
1 | Q9VE86 (/IC) |
|
DNA catabolic process, exonucleolytic GO:0000738
The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
|
1 | Q9VE86 (/IDA) |
|
Negative regulation of mitotic recombination GO:0045950
Any process that inhibits or decreases the rate of DNA recombination during mitosis.
|
1 | Q9VE86 (/IMP) |
|
Replication fork protection GO:0048478
Any process that prevents the collapse of stalled replication forks.
|
1 | Q9VE86 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
B3LWP6 (/ISS)
B3NZ68 (/ISS)
B4G5C9 (/ISS)
B4I298 (/ISS)
B4JF25 (/ISS)
B4K934 (/ISS)
B4M401 (/ISS)
B4N9D3 (/ISS)
B4PLB3 (/ISS)
B4QUF6 (/ISS)
(1 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9VE86 (/IDA) |
