The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Protein argonaute-2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Argonaute-2. [EC: 3.1.26.n2]
Endonucleolytic cleavage to 5'-phosphomonoester.
  • The enzyme, isolated from animals, is required for RNA-mediated gene silencing (RNAi).
375 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34 A0A096MU34
(365 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...