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CATH Superfamily 3.30.390.30

FAD/NAD-linked reductase, C-terminal dimerisation domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Flavoprotein disulfide reductaseTrypanothione reductaseSC:2Putative apoptosis-inducing factor 1, mitochondrialMonodehydroascorbate reductase 3Putidaredoxin reductase CamANADH-rubredoxin oxidoreductaseDihydrolipoyl dehydrogenaseSoluble pyridine nucleotide transhydrogenaseGlutathione reductaseThioredoxin reductase 1, cytoplasmicNitrite reductase large subunitGlutathione reductasePyridine nucleotide-disulfide oxidoreductase domain-containing protein 13-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase componentApoptosis-inducing factor, mitochondrion-associated, 3Putative dihydrolipoamide dehydrogenaseGlutathione reductaseNitrite reductase large subunitMycothione reductaseMonodehydroascorbate reductaseLipoamide dehydrogenaseGlutathione reductaseNitrite reductase large subunitFerredoxin reductaseGlutathione reductaseGlutathione-disulfide reductaseIrc15pNitrite reductase [NAD(P)H], large subunitRubredoxin-NAD(+) reductaseFAD-dependent pyridine nucleotide-disulphide oxidoreductaseUncharacterized proteinGlutathione reductasePyridine nucleotide-disulfide oxidoreductasePutative pyridine nucleotide-disulfide oxidoreductasePyridine nucleotide-disulfide oxidoreductaseWorm AIF (Apoptosis inducing factor) HomologMercuric reductaseGlutathione reductaseGlutathione reductaseBis-gamma-glutamylcystine reductaseNitrate reductase, NADH oxidase subunitIP11909pMercuric reductase, putativeGlutathione reductaseGlutathione reductaseGlr2871 proteinUncharacterized proteinApoptosis-inducing factor 1, mitochondrialGlutathione reductaseFAD-dependent pyridine nucleotide-disulphide oxidoreductaseGlutathione reductasePredicted protein
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FunFam 20: Lipoamide dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Dihydrolipoyl dehydrogenase activity GO:0004148
Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.
 2 Q8IAZ6 (/IDA) Q8IAZ6 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
 2 Q8IAZ6 (/IDA) Q8IAZ6 (/IDA)
Cofactor binding GO:0048037
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
 2 Q8IAZ6 (/IDA) Q8IAZ6 (/IDA)
Showing 1 to 3 of 3 entries

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Acetyl-CoA biosynthetic process from pyruvate GO:0006086
The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
 2 Q8IAZ6 (/IMP) Q8IAZ6 (/IMP)
Showing 1 to 1 of 1 entries

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
 2 Q8IAZ6 (/IDA) Q8IAZ6 (/IDA)
Showing 1 to 1 of 1 entries
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