The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
K Homology domain, type 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 78: Uncharacterized protein, isoform A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
6 A1ZBW0 (/HMP) A1ZBW1 (/HMP) E1JGN7 (/HMP) Q7KA80 (/HMP) Q7KHL0 (/HMP) Q9V948 (/HMP)
Imaginal disc growth GO:0007446
The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Appendage morphogenesis GO:0035107
The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
6 A1ZBW0 (/IDA) A1ZBW1 (/IDA) E1JGN7 (/IDA) Q7KA80 (/IDA) Q7KHL0 (/IDA) Q9V948 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A1ZBW0 (/HDA) A1ZBW1 (/HDA) E1JGN7 (/HDA) Q7KA80 (/HDA) Q7KHL0 (/HDA) Q9V948 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A1ZBW0 (/IC) A1ZBW1 (/IC) E1JGN7 (/IC) Q7KA80 (/IC) Q7KHL0 (/IC) Q9V948 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A1ZBW0 (/IDA) A1ZBW1 (/IDA) E1JGN7 (/IDA) Q7KA80 (/IDA) Q7KHL0 (/IDA) Q9V948 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 A1ZBW0 (/TAS) A1ZBW1 (/TAS) E1JGN7 (/TAS) Q7KA80 (/TAS) Q7KHL0 (/TAS) Q9V948 (/TAS)
Omega speckle GO:0035062
A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).
6 A1ZBW0 (/IDA) A1ZBW1 (/IDA) E1JGN7 (/IDA) Q7KA80 (/IDA) Q7KHL0 (/IDA) Q9V948 (/IDA)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
6 A1ZBW0 (/ISS) A1ZBW1 (/ISS) E1JGN7 (/ISS) Q7KA80 (/ISS) Q7KHL0 (/ISS) Q9V948 (/ISS)
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