The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
K Homology domain, type 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: protein quaking isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 D4YW53 (/IPI) G5EFF1 (/IPI) Q17339 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI) Q96PU8 (/IPI)
(18 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
25 Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA) Q96PU8 (/HDA)
(15 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
25 Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS)
(15 more)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
3 D4YW53 (/IDA) G5EFF1 (/IDA) Q17339 (/IDA)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
3 O01367 (/IDA) O01367 (/IDA) Q17339 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 O01367 (/IDA) O01367 (/IDA)
Pre-mRNA intronic binding GO:0097157
Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA).
2 D4YW53 (/IPI) G5EFF1 (/IPI)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
1 Q32NN2 (/IMP)
Poly(U) RNA binding GO:0008266
Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule.
1 Q32NN2 (/IMP)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q32NN2 (/IMP)
Showing 1 to 10 of 11 entries

There are 54 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Axon ensheathment GO:0008366
Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
27 O01367 (/IMP) O01367 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(17 more)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
25 Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(15 more)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
25 Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO)
(15 more)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
25 Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI) Q9QYS9 (/IGI)
(15 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
25 Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(15 more)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
25 Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO)
(15 more)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
25 Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO)
(15 more)
Myelination GO:0042552
The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
25 Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(15 more)
Muscle cell differentiation GO:0042692
The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
25 Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(15 more)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
25 Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(15 more)
Showing 1 to 10 of 54 entries

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
30 D4YW53 (/IDA) G5EFF1 (/IDA) O01367 (/IDA) O01367 (/IDA) Q91XU1 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA)
(20 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
28 O01367 (/IDA) O01367 (/IDA) Q17339 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA)
(18 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
26 Q32NN2 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP) Q9QYS9 (/IMP)
(16 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
25 Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO) Q9QYS9 (/ISO)
(15 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
25 Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS)
(15 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
25 Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS) Q9QYS9 (/TAS)
(15 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
25 Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP) Q9QYS9 (/EXP)
(15 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
25 Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA) Q9QYS9 (/IDA)
(15 more)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
3 D4YW53 (/IDA) G5EFF1 (/IDA) Q17339 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O01367 (/IC) O01367 (/IC)
Showing 1 to 10 of 14 entries
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