The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)met...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity GO:0003949
Catalysis of the reaction: 1-(5-phosphoribosyl)-5-
11 P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA)
(1 more)
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity GO:0003949
Catalysis of the reaction: 1-(5-phosphoribosyl)-5-
9 Q3Z6V7 (/ISS) Q5LR59 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
11 P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA)
(1 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
11 P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP) P10371 (/IEP)
(1 more)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
9 Q3Z6V7 (/ISS) Q5LR59 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS) Q9KSW9 (/ISS)
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
6 P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP)
Tryptophan biosynthetic process GO:0000162
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
6 P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP) P9WMM5 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA) P10371 (/IDA)
(1 more)
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