The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)met...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase. [EC: 5.3.1.16]
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D- ribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1- deoxy-D-ribulos-1-ylamino)methylideneamino)-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide.
  • Involved in histidine biosynthesis.
5823 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4 A0A023P3Q4
(5813 more...)
Phosphoribosylanthranilate isomerase. [EC: 5.3.1.24]
N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1- deoxy-D-ribulose 5-phosphate.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 4.2.1.20).
128 A0A062WA62 A0A062WA62 A0A062WA62 A0A062WA62 A0A062WA62 A0A062WA62 A0A0H3L8U4 A0A0H3L8U4 A0A0H3L8U4 A0A0H3L8U4
(118 more...)
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