The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Dynein heavy chain, cytoplasmic

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retrograde axonal transport GO:0008090
The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.
1 Q19020 (/IMP)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
1 Q19020 (/IMP)
Synaptic vesicle transport GO:0048489
The directed movement of synaptic vesicles.
1 Q19020 (/IMP)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
1 Q19020 (/IGI)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
1 Q19020 (/IMP)
Establishment of spindle localization GO:0051293
The directed movement of the spindle to a specific location in the cell.
1 Q19020 (/IMP)
Establishment of meiotic spindle orientation GO:0051296
Any process that set the alignment of meiotic spindle relative to other cellular structures.
1 Q19020 (/IGI)
Establishment of meiotic spindle orientation GO:0051296
Any process that set the alignment of meiotic spindle relative to other cellular structures.
1 Q19020 (/IMP)
Maintenance of centrosome location GO:0051661
Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.
1 Q19020 (/IMP)
Synaptic transmission, GABAergic GO:0051932
The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q19020 (/IGI)
Synaptic transmission, GABAergic GO:0051932
The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q19020 (/IMP)
Regulation of protein localization to synapse GO:1902473
Any process that modulates the frequency, rate or extent of protein localization to synapse.
1 Q19020 (/IMP)
Positive regulation of dense core granule transport GO:1904811
Any process that activates or increases the frequency, rate or extent of dense core granule transport.
1 Q19020 (/IMP)
Anterograde neuronal dense core vesicle transport GO:1990048
The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.
1 Q19020 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
1 Q19020 (/IDA)
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 Q19020 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 Q19020 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q19020 (/IDA)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
1 Q19020 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 Q19020 (/IDA)
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