The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: heat shock protein 27

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
7 P02516 (/ISM) P02516 (/ISM) P02517 (/ISM) P02517 (/ISM) P02518 (/ISM) P02518 (/ISM) P05812 (/ISM)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
6 P02516 (/IDA) P02516 (/IDA) P02517 (/IDA) P02517 (/IDA) P02518 (/IDA) P02518 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P02516 (/IPI) P02516 (/IPI) P02518 (/IPI) P02518 (/IPI)
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
2 P02517 (/IPI) P02517 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
7 P02516 (/IDA) P02516 (/IDA) P02517 (/IDA) P02517 (/IDA) P02518 (/IDA) P02518 (/IDA) P05812 (/IDA)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
7 P02516 (/ISM) P02516 (/ISM) P02517 (/ISM) P02517 (/ISM) P02518 (/ISM) P02518 (/ISM) P05812 (/ISM)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
6 P02516 (/IDA) P02516 (/IDA) P02517 (/IDA) P02517 (/IDA) P02518 (/IDA) P02518 (/IDA)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
6 P02516 (/IDA) P02516 (/IDA) P02517 (/IDA) P02517 (/IDA) P02518 (/IDA) P02518 (/IDA)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
4 P02517 (/IMP) P02517 (/IMP) P02518 (/IMP) P02518 (/IMP)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
4 P02516 (/IEP) P02516 (/IEP) P02517 (/IEP) P02517 (/IEP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P02516 (/IEP) P02516 (/IEP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P02516 (/IMP) P02516 (/IMP)
Behavioral response to starvation GO:0042595
Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.
2 P02518 (/IMP) P02518 (/IMP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
2 P02518 (/IMP) P02518 (/IMP)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 P02518 (/IMP) P02518 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P02517 (/HDA) P02517 (/HDA) P02518 (/HDA) P02518 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P02518 (/HDA) P02518 (/HDA)
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