The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: Heat shock protein beta-8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
18 Q9JK92 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI)
(8 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
17 Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI) Q9UJY1 (/IPI)
(7 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9JK92 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9JK92 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
17 Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP)
(7 more)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
17 Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS)
(7 more)
Positive regulation of aggrephagy GO:1905337
Any process that activates or increases the frequency, rate or extent of aggrephagy.
17 Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP) Q9UJY1 (/IMP)
(7 more)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
1 Q9JK92 (/ISO)
Positive regulation of aggrephagy GO:1905337
Any process that activates or increases the frequency, rate or extent of aggrephagy.
1 Q9JK92 (/ISO)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
24 Q5EAC9 (/ISS) Q5EAC9 (/ISS) Q5EAC9 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS)
(14 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
24 Q5EAC9 (/ISS) Q5EAC9 (/ISS) Q5EAC9 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS) Q5RAB0 (/ISS)
(14 more)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
17 Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS) Q9UJY1 (/TAS)
(7 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Chaperone complex GO:0101031
A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
17 Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA) Q9UJY1 (/IDA)
(7 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JK92 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9JK92 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9JK92 (/ISO)
Chaperone complex GO:0101031
A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
1 Q9JK92 (/ISO)
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