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CATH Superfamily 2.10.25.10

Laminin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 930: Meprin A subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Meprin A. [EC: 3.4.24.18]
Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.
  • A membrane-bound metalloendopeptidase of rat and mouse kidney and intestinal brush borders, and salivary ducts.
  • Differences from EC 3.4.24.11 include insensitivity to phosphoramidon and thiorphan.
  • PABA-peptide hydrolase is a very similar enzyme found in human intestinal microvilli.
  • Belongs to peptidase family M12A.
 1 P28825
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