The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 210: Hemicentin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
4 M9NE82 (/ISM) M9NE82 (/ISM) M9PB31 (/ISM) M9PB31 (/ISM)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 Q96RW7 (/HDA)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 D3YXG0 (/RCA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
4 M9NE82 (/IMP) M9NE82 (/IMP) M9PB31 (/IMP) M9PB31 (/IMP)
Apposition of dorsal and ventral imaginal disc-derived wing surfaces GO:0007475
The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
4 M9NE82 (/IMP) M9NE82 (/IMP) M9PB31 (/IMP) M9PB31 (/IMP)
Chitin-based embryonic cuticle biosynthetic process GO:0008362
Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.
4 M9NE82 (/IMP) M9NE82 (/IMP) M9PB31 (/IMP) M9PB31 (/IMP)
Chitin-based cuticle attachment to epithelium GO:0040005
Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.
4 M9NE82 (/IMP) M9NE82 (/IMP) M9PB31 (/IMP) M9PB31 (/IMP)
Regulation of imaginal disc-derived wing size GO:0044719
Any process that modulates the size of an imaginal disc-derived wing.
4 M9NE82 (/IMP) M9NE82 (/IMP) M9PB31 (/IMP) M9PB31 (/IMP)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
2 E7F3V2 (/IGI) M9MMB9 (/IGI)
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
2 F1QVQ2 (/IMP) F1R7R3 (/IMP)
Fin morphogenesis GO:0033334
The process in which the anatomical structures of a fin are generated and organized.
2 F1QVQ2 (/IMP) F1R7R3 (/IMP)
Embryonic medial fin morphogenesis GO:0035122
The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
2 E7F3V2 (/IGI) M9MMB9 (/IGI)
Skin morphogenesis GO:0043589
The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
2 E7F3V2 (/IGI) M9MMB9 (/IGI)
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
2 F1QVQ2 (/IMP) F1R7R3 (/IMP)
Mesenchymal cell migration GO:0090497
The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.
2 E7F3V2 (/IGI) M9MMB9 (/IGI)
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
1 A7MD60 (/IGI)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 D3YXG0 (/IEP)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A7MD60 (/IDA)
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
1 A7MD60 (/IGI)
Primitive hemopoiesis GO:0060215
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
1 A7MD60 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
4 M9NE82 (/ISM) M9NE82 (/ISM) M9PB31 (/ISM) M9PB31 (/ISM)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 D3YXG0 (/HDA) Q96RW7 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 D3YXG0 (/IDA)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
1 D3YXG0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 A7MD60 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 D3YXG0 (/IDA)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
1 D3YXG0 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q96RW7 (/HDA)
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