The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Laminin
".
FunFam 128: laminin subunit alpha-2 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P19137 (/IPI) P19137 (/IPI) P25391 (/IPI) P25391 (/IPI) P98160 (/IPI) Q05793 (/IPI) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
5 | P19137 (/RCA) P19137 (/RCA) P24043 (/RCA) P24043 (/RCA) Q60675 (/RCA) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
3 | P25391 (/IPI) P25391 (/IPI) P98160 (/IPI) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
3 | P19137 (/ISO) P19137 (/ISO) Q05793 (/ISO) |
Extracellular matrix structural constituent conferring compression resistance GO:0030021
A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.
|
3 | F1SU03 (/RCA) P98160 (/RCA) Q05793 (/RCA) |
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
|
2 | P24043 (/TAS) P24043 (/TAS) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
2 | P25391 (/ISS) P25391 (/ISS) |
Glycosphingolipid binding GO:0043208
Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
1 | P98160 (/IC) |
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
|
1 | Q05793 (/IPI) |
Extracellular matrix structural constituent conferring compression resistance GO:0030021
A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.
|
1 | P98160 (/ISS) |
Low-density lipoprotein particle receptor binding GO:0050750
Interacting selectively and non-covalently with a low-density lipoprotein receptor.
|
1 | P98160 (/TAS) |
There are 46 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
5 | P24043 (/TAS) P24043 (/TAS) P25391 (/TAS) P25391 (/TAS) P98160 (/TAS) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
4 | A0A0R4IZA6 (/IMP) B2RZI0 (/IMP) F1R5K7 (/IMP) F1RCP6 (/IMP) |
Endothelial cell proliferation GO:0001935
The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
|
4 | A0A0R4IZA6 (/IMP) B2RZI0 (/IMP) F1R5K7 (/IMP) F1RCP6 (/IMP) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
4 | A0A0G2KI51 (/IMP) G8IHT9 (/IMP) G8IHT9 (/IMP) G8IHU0 (/IMP) |
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
|
4 | A0A0R4IZA6 (/IMP) B2RZI0 (/IMP) F1R5K7 (/IMP) F1RCP6 (/IMP) |
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
4 | A0A0G2KI51 (/IGI) G8IHT9 (/IGI) G8IHT9 (/IGI) G8IHU0 (/IGI) |
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
4 | A0A0G2KI51 (/IMP) G8IHT9 (/IMP) G8IHT9 (/IMP) G8IHU0 (/IMP) |
Myelination in peripheral nervous system GO:0022011
The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
|
4 | A0A0G2KI51 (/IGI) G8IHT9 (/IGI) G8IHT9 (/IGI) G8IHU0 (/IGI) |
Blood vessel endothelial cell migration GO:0043534
The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
|
4 | A0A0R4IZA6 (/IMP) B2RZI0 (/IMP) F1R5K7 (/IMP) F1RCP6 (/IMP) |
Skeletal muscle organ development GO:0060538
The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.
|
4 | A0A0G2KI51 (/IMP) G8IHT9 (/IMP) G8IHT9 (/IMP) G8IHU0 (/IMP) |
Morphogenesis of an epithelial sheet GO:0002011
The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
2 | P25391 (/ISS) P25391 (/ISS) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
2 | P24043 (/TAS) P24043 (/TAS) |
Tissue development GO:0009888
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
2 | P19137 (/IDA) P19137 (/IDA) |
Establishment of epithelial cell apical/basal polarity GO:0045198
The specification and formation of the apicobasal polarity of an epithelial cell.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Epithelial tube branching involved in lung morphogenesis GO:0060441
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Branching involved in salivary gland morphogenesis GO:0060445
The process in which the branching structure of the salivary gland is generated and organized.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Retinal blood vessel morphogenesis GO:0061304
The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.
|
2 | P19137 (/IMP) P19137 (/IMP) |
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
|
1 | P98160 (/TAS) |
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
|
1 | Q05793 (/IMP) |
Chondrocyte differentiation GO:0002062
The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
|
1 | Q05793 (/IMP) |
Glycosaminoglycan biosynthetic process GO:0006024
The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
|
1 | P98160 (/TAS) |
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
|
1 | P98160 (/TAS) |
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
1 | P98160 (/TAS) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | Q05793 (/IGI) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | Q05793 (/IMP) |
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | P98160 (/ISS) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | P98160 (/TAS) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q60675 (/IGI) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q05793 (/IMP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | P98160 (/TAS) |
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q05793 (/IMP) |
Schwann cell differentiation GO:0014037
The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
|
1 | F1M614 (/IEP) |
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | P98160 (/TAS) |
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
1 | P98160 (/TAS) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | Q05793 (/IMP) |
Positive regulation of synaptic transmission, cholinergic GO:0032224
Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
|
1 | Q60675 (/IMP) |
Cellular protein metabolic process GO:0044267
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
|
1 | P98160 (/TAS) |
Embryonic skeletal system morphogenesis GO:0048704
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
|
1 | Q05793 (/IMP) |
Cardiac muscle tissue development GO:0048738
The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
|
1 | Q05793 (/IMP) |
Cartilage development involved in endochondral bone morphogenesis GO:0060351
The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.
|
1 | Q05793 (/IMP) |
Cardiovascular system development GO:0072358
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
|
1 | P98160 (/TAS) |
There are 31 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
9 | P19137 (/TAS) P19137 (/TAS) P24043 (/TAS) P24043 (/TAS) P25391 (/TAS) P25391 (/TAS) P98160 (/TAS) Q05793 (/TAS) Q60675 (/TAS) |
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
9 | F1M614 (/IDA) P19137 (/IDA) P19137 (/IDA) P24043 (/IDA) P24043 (/IDA) P25391 (/IDA) P25391 (/IDA) Q05793 (/IDA) Q60675 (/IDA) |
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
|
9 | P19137 (/HDA) P19137 (/HDA) P24043 (/HDA) P24043 (/HDA) P25391 (/HDA) P25391 (/HDA) P98160 (/HDA) Q05793 (/HDA) Q60675 (/HDA) |
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
6 | F1LTJ5 (/TAS) P19137 (/TAS) P19137 (/TAS) P24043 (/TAS) P24043 (/TAS) P98160 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
5 | P19137 (/HDA) P19137 (/HDA) P98160 (/HDA) Q05793 (/HDA) Q60675 (/HDA) |
Laminin-1 complex GO:0005606
A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
|
4 | P19137 (/IDA) P19137 (/IDA) P25391 (/IDA) P25391 (/IDA) |
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
3 | P19137 (/ISO) P19137 (/ISO) Q60675 (/ISO) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
3 | P19137 (/IDA) P19137 (/IDA) Q05793 (/IDA) |
Laminin-1 complex GO:0005606
A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
|
2 | P25391 (/IPI) P25391 (/IPI) |
Laminin-1 complex GO:0005606
A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
|
2 | P19137 (/ISO) P19137 (/ISO) |
Laminin-3 complex GO:0005608
A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
|
2 | P25391 (/IPI) P25391 (/IPI) |
Laminin-3 complex GO:0005608
A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
|
2 | P19137 (/ISO) P19137 (/ISO) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P25391 (/IDA) P25391 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P19137 (/ISO) P19137 (/ISO) |
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
|
2 | P98160 (/TAS) Q05793 (/TAS) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P25391 (/IDA) P25391 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P19137 (/ISO) P19137 (/ISO) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
2 | P25391 (/ISS) P25391 (/ISS) |
Laminin complex GO:0043256
A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.
|
2 | P19137 (/IDA) P19137 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P98160 (/HDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P98160 (/TAS) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | P98160 (/HDA) |
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
|
1 | Q60675 (/IDA) |
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
|
1 | Q60675 (/IDA) |
Synaptic cleft GO:0043083
The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
|
1 | Q60675 (/IDA) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
1 | F1M614 (/IDA) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
1 | Q60675 (/ISO) |
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
|
1 | P98160 (/TAS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P98160 (/HDA) |
Plasma membrane protein complex GO:0098797
Any protein complex that is part of the plasma membrane.
|
1 | P98160 (/TAS) |