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CATH Superfamily 1.20.900.10

Dbl homology (DH) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Dbl homology (DH) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Rho guanine nucleotide exchange factor 2Rho guanine nucleotide exchange factor (GEF) 11rho guanine nucleotide exchange factor 25Rho guanine nucleotide exchange factor 3 isoform 1Intersectin 1T cell lymphoma invasion and metastasis 1Rho guanine nucleotide exchange factor 6Phosphatidylinositol-3,4, 5-trisphosphate-dependent Rac exchange factor 2, putativeSC:2son of sevenless homolog 1 isoform X1FERM, RhoGEF and pleckstrin domain-containing protein 2FYVE, RhoGEF and PH domain-containing protein 6Guanine nucleotide exchange factor DBSRho guanine nucleotide exchange factor 9Rho guanine nucleotide exchange factor 10 likeRas-specific guanine nucleotide-releasing factor 1 isoform 2rho guanine nucleotide exchange factor 19Vav guanine nucleotide exchange factor 1FYVE, RhoGEF and PH domain-containing protein 4active breakpoint cluster region-related protein isoform X2pleckstrin homology domain-containing family G member 5 isoform X1Pleckstrin homology domain-containing family G member 1FERM, RhoGEF and pleckstrin domain-containing protein 1protein ECT2 isoform X1dynamin-binding protein isoform X2Rho guanine nucleotide exchange factor 17Alsin isoform X1Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEFPuratrophin-1-like, isoform DRho guanine nucleotide exchange factor 37rho guanine nucleotide exchange factor 39Uncharacterized protein, isoform Brho guanine nucleotide exchange factor 38Muscle M-line assembly protein unc-89-like ProteinUncharacterized protein, isoform BRho guanyl nucleotide exchange factorEG:23E12.2, isoform BProtostome-specific GEF, isoform CMyosin-M heavy chainUncharacterized protein, isoform CTrio, isoform DRho guanyl nucleotide exchange factoruncharacterized protein LOC108093793 isoform X3ALS2 C-terminal likeUncharacterized protein, isoform BUncharacterized protein, isoform CRelated to CDC24-GTP/GDP exchange factor for Cdc42pUncharacterized protein, isoform AGL21162Rho guanine nucleotide exchange factor 38Guanine nucleotide exchange factorPhosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1Cell division control protein 24Rho guanyl nucleotide exchange factor, putativeCDC-42 Guanine nucleotide Exchange FactorUNC-112-Interacting Guanine nucleotide exchange factorTOR unique function suppressorRho guanine nucleotide exchange factor 38Uncharacterized protein, isoform AProtein CBG22463Rho guanine nucleotide exchange factor osg-1TIAM (Mammalian Tumor Invasion And Metastasis factor) homologUnplaced genomic scaffold supercont1.14, whole genome shotgun sequenceRho guanine nucleotide exchange factor (GEF) 37Muscle M-line assembly protein unc-89T-cell activation Rho GTPase activating protein, putativeRhoGAP domain containing proteinRho guanyl nucleotide exchange factor, putative (AFU_orthologue AFUA_5G11890)FUS2p Cell fusion regulatorUncharacterized proteinFERM domain (Protein4.1-ezrin-radixin-moesin) familyPhosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform aPutative Rho guanine nucleotide exchange factor FGD-1Putative RhoGEF group proteinRHo Guanine nucleotide exchange FactorRho guanine nucleotide exchange factor 38Uncharacterized proteinUncharacterized proteinGuanine nucleotide exchange factor UNC-73BObscurinFERM, ARHGEF and pleckstrin domain-containing protein 1Protein ECT2Uncharacterized proteinObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF aKalirin RhoGEF kinase aUncharacterized proteinUncharacterized proteinFERM, ARH/RhoGEF and pleckstrin domain protein 2Putative rho guanine nucleotide exchange factor cdepPIX (PAK (p21-activated kinase) Interacting eXchange factor) homologYALI0F13673pPhosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2Son of sevenless homologECT2 (Mammalian Rho GEF) homologDynamin-binding proteinRho GTPase-activating protein 20Uncharacterized proteinMKIAA1209 proteinAT26020pRho1 guanine nucleotide exchange factor 3Uncharacterized proteinRho guanine nucleotide exchange factor (GEF) 26MKIAA0380 proteinMeiotically up-regulated gene 10 proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinGH01987pProtein CBG05206RH56938pChromosome 7, whole genome shotgun sequenceUncharacterized proteinPhosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1Rho guanine nucleotide exchange factor gef2Rac guanine nucleotide exchange factor BUncharacterized proteinUncharacterized proteinRho guanine nucleotide exchange factor 37Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF bUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinKalirin RhoGEF kinase aUncharacterized proteinSon of sevenless 1Predicted proteinRho GTPase regulating protein, putativeUncharacterized proteinPredicted proteinProbable serine/threonine-protein kinase roco5BAR domaincontaining proteinPredicted proteinPredicted protein
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FunFam 120: Rho guanine nucleotide exchange factor 37

GO Diversity

Unique GO annotations
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0 Unique GO terms

EC Diversity

Unique EC annotations
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0 Unique EC terms

Species Diversity

Unique species annotations
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1 Unique species

Statistics

Members
CATH Domains: 0
Sequences: 1
Annotations
Unique GO:
Unique EC: 0
Unique Species: 1
Representative
Rep ID: F7BH03/1-195
Inherited Annotations: 0
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