CATH Domain 6i7nB03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.390	Enolase-like; domain 1
	3.30.390.30	FAD/NAD-linked reductase, C-terminal dimerisation domain

Domain Context

CATH Clusters

Superfamily	3.30.390.30
Functional Family	Trypanothione reductase

Enzyme Information

UniProtKB Entries (1)

A4HSF7_LEIIN

Leishmania infantum

Trypanothione reductase

PDB Structure

PDB	6I7N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase. Revuelto, A., Ruiz-Santaquiteria, M., de Lucio, H., Gamo, A., Carriles, A.A., Gutierrez, K.J., Sanchez-Murcia, P.A., Hermoso, J.A., Gago, F., Camarasa, M.J., Jimenez-Ruiz, A., Velazquez, S. Acs Infect Dis.