CATH Domain 4i5sA03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.287	Helix Hairpins
	1.10.287.130	Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain

Domain Context

CATH Clusters

Superfamily	1.10.287.130
Functional Family	Two-component sensor histidine kinase

Enzyme Information

UniProtKB Entries (1)

Q8DT64_STRMU

Streptococcus mutans UA159

Putative histidine kinase CovS VicK-like protein

PDB Structure

PDB	4I5S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains Wang, C., Sang, J., Wang, J., Su, M., Downey, J.S., Wu, Q., Wang, S., Cai, Y., Xu, X., Wu, J., Senadheera, D.B., Cvitkovitch, D.G., Chen, L., Goodman, S.D., Han, A. Plos Biol.