The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Helix-loop-helix DNA-binding domain
".
FunFam 99: Myc-family transcription factor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
4 | P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P07270 (/IPI) P07270 (/IPI) P07270 (/IPI) P07270 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
4 | P07270 (/HDA) P07270 (/HDA) P07270 (/HDA) P07270 (/HDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
4 | P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | C8V3P3 (/ISS) C8V3P3 (/ISS) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
|
5 | A0A1D8PMD1 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | A0A1D8PMD1 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
4 | P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) P07270 (/IMP) |
|
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
|
4 | P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) |
|
Positive regulation of phosphate metabolic process GO:0045937
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
|
4 | P07270 (/IGI) P07270 (/IGI) P07270 (/IGI) P07270 (/IGI) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | P07270 (/IGI) P07270 (/IGI) P07270 (/IGI) P07270 (/IGI) |
|
Cellular phosphate ion homeostasis GO:0030643
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
|
2 | C8V3P3 (/IGI) C8V3P3 (/IGI) |
|
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
1 | A0A1D8PMD1 (/IMP) |
|
Cellular metal ion homeostasis GO:0006875
Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
|
1 | A0A1D8PMD1 (/IMP) |
|
Positive regulation of phosphatase activity GO:0010922
Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
1 | Q6FVW0 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | A0A1D8PMD1 (/IMP) |
|
Cellular phosphate ion homeostasis GO:0030643
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
|
1 | A0A1D8PMD1 (/IMP) |
|
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | A0A1D8PMD1 (/IMP) |
|
Cellular response to arsenic-containing substance GO:0071243
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
|
1 | A0A1D8PMD1 (/IMP) |
|
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | A0A1D8PMD1 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | A0A1D8PMD1 (/IDA) P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) Q6FVW0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) P07270 (/IDA) Q6FVW0 (/IDA) |
