CATH Superfamily 4.10.280.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Putative transcription factor 12	1647	3D	2ql2C00	-	82.4
2	Basic helix-loop-helix transcription factor	1394		-	-	89.3
3	microphthalmia-associated transcription factor isoform X1	1290	3D	6g1lA00	-	76.9
4	Basic helix-loop-helix transcription factor	891		-	-	91.4
5	Myogenic factor	808	3D	1mdyD00	-	90.0
6	Neurogenic differentiation factor	771	3D	2ql2D00	-	73.4
7	single-minded homolog 1 isoform X1	730		-	-	80.5
8	Nuclear receptor coactivator	724		-	-	91.8
9	Transcription factor HES-1	686		-	-	86.0
10	Scleraxis bHLH transcription factor	668		-	-	86.4
11	Aryl hydrocarbon receptor nuclear translocator 2	608		-	-	57.8
12	hairy/enhancer-of-split related with YRPW motif protein 1	583		-	-	76.7
13	Circadian locomoter output cycles protein kaput	561	3D	4f3lA01	-	85.7
14	Max dimerization protein 1	484	3D	1nlwD00	-	74.7
15	T-cell acute lymphocytic leukemia 1	472	3D	2ypbA00	-	82.0
16	Sterol regulatory element-binding transcription factor 1	471	3D	1am9D00	-	77.5
17	Transcription factor bHLH66	446		-	-	84.8
18	Aryl hydrocarbon receptor nuclear translocator-like protein 1	442	3D	4f3lB01	-	71.4
19	Myc proto-oncogene protein	427	3D	5i50B00	-	98.9
20	class E basic helix-loop-helix protein 40	344		-	-	68.9
23	MAX isoform 13	316	3D	5eyoC00	-	78.8
21	Transcription factor bHLH130 family	315		-	-	82.4
22	Basic helix-loop-helix transcription factor	308		-	-	86.8
24	Aryl hydrocarbon receptor 2	290		-	-	71.1
25	protein atonal homolog 7	282		-	-	70.7
26	Basic helix-loop-helix family, member e23	281		-	-	66.0
27	Nescient helix-loop-helix 1	279		-	-	63.3
28	MLX interacting protein like	275		-	-	93.8
29	Achaete-scute family bHLH transcription factor 1	257		-	-	83.5
30	Twist transcription factor	256		-	-	64.5
31	Oligodendrocyte transcription factor 3	233		-	-	61.7
32	Transcription factor bHLH123 family	223		-	-	82.1
33	Transcription factor HES-5	220		-	-	87.4
34	MAX network transcriptional repressor	217		-	-	83.1
35	Pancreas-specific transcription factor 1a	214		-	-	73.6
36	Transcription factor AP-4	212		-	-	71.4
37	max-like protein X isoform X2	199		-	-	77.2
38	achaete-scute homolog 3	192		-	-	74.4
39	DNA-binding protein inhibitor ID-3	189	3D	2lfhB00	-	82.1
40	MAX gene-associated protein isoform X1	175		-	-	80.1
41	aryl hydrocarbon receptor repressor	169		-	-	72.8
42	transcription factor bHLH48-like isoform X1	165		-	-	50.9
43	Helix-loop-helix DNA binding protein	163		-	-	31.0
44	Basic helix-loop-helix transcription factor	157		-	-	58.5
45	upstream stimulatory factor 2 isoform X1	153		-	-	39.4
46	Transcription factor bHLH83	143		-	-	81.4
47	mesoderm posterior protein 1	141		-	-	68.0
49	MAX isoform 16	131	3D	1hloB00	-	24.7
48	DNA-binding protein inhibitor ID-4	129		-	-	79.9
50	Basic helix-loop-helix transcription factor	128		-	-	69.1
51	Basic helix-loop-helix domain-containing protein KIAA2018	115		-	-	85.9
52	Protein atonal homolog 8	114		-	-	88.6
53	BHLH transcription factor	113		-	-	73.0
54	hairy and enhancer of split-related protein HELT	112		-	-	80.3
55	DNA-binding protein inhibitor ID-2	109	3D	4ayaB00	-	49.3
56	mesogenin-1	106		-	-	57.6
58	transcription factor BEE 3-like	100		-	-	64.8
57	transcription factor-like 5 protein-like	100		-	-	86.9
59	transcription factor UNE10 isoform X1	100		-	-	75.2
60	Scute protein	95		-	-	69.4
61	Transcription factor SPEECHLESS	88		-	-	69.0
62	Neuronal PAS domain-containing protein 3	88		-	-	85.9
63	transcription factor HES-7 isoform X1	86		-	-	88.8
64	Transcription factor MUTE	85		-	-	66.7
65	class A basic helix-loop-helix protein 15	81		-	-	50.7
66	BHLH transcription factor	80		-	-	72.7
67	upstream stimulatory factor 1 isoform X1	76		-	-	23.1
68	factor in the germline alpha	70		-	-	78.0
69	Transcription factor PIF7	65		-	-	78.4
70	transcription factor bHLH30	63		-	-	79.1
71	spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2	61		-	-	73.2
72	enhancer of split mgamma protein-like	52		-	-	44.7
74	Transcription factor ORG2	51		-	-	91.4
73	MAX dimerization protein 3	51		-	-	42.4
75	Transcription factor bHLH113 family	48		-	-	79.3
76	hypoxia-inducible factor 3-alpha isoform X1	47		-	-	69.0
77	transcription factor HES-3 isoform X2	45		-	-	77.5
78	Transcription factor bHLH13	44		-	-	66.0
79	CLUMA_CG001539, isoform A	43		-	-	77.8
80	Taiman isoform A	41		-	-	88.3
82	Transcription factor ILI6	40		-	-	66.2
81	transcription cofactor HES-6 isoform X1	40		-	-	85.3
83	Neuronal PAS domain protein 1	40		-	-	72.2
84	class A basic helix-loop-helix protein 9	37		-	-	43.3
85	Transcription factor bHLH126	37		-	-	91.9
86	protein extra-macrochaetae	37		-	-	73.7
87	Transcription factor hes-1	36		-	-	63.1
89	Transcription factor LAX PANICLE	35		-	-	70.4
88	HLH DNA binding protein	35		-	-	23.1
90	Salivary gland-expressed bHLH	32		-	-	82.8
99	Myc-family transcription factor	31	3D	1a0aB00	-	76.3
91	HLH DNA binding domain protein	30		-	-	35.1
92	transcription factor bHLH68 isoform X1	30		-	-	36.7
93	BHLH domain class transcription factor	30		-	-	56.0
94	Blast:Carbohydrate-responsive element-binding protein	30		-	-	67.5
96	Basic helix-loop-helix BHLH	29		-	-	82.3
95	Basic helix-loop-helix family protein	29		-	-	73.2
98	Sterol regulatory element-binding protein	29		-	-	69.8
97	Neuronal PAS domain-containing protein 2	29		-	-	57.2
102	Nescient helix-loop-helix 1	27		-	-	58.5
100	Transcription factor BEE 3	27		-	-	59.2
101	Transcription factor PRE4	27		-	-	52.9
103	Transcription factor bHLH162	25		-	-	87.3
104	Transcription factor bHLH34	25		-	-	80.5
105	Rtg3p	24		-	-	67.2
106	Transcription factor ILI5	22		-	-	27.7
107	Basic helix-loop-helix transcription factor	22		-	-	38.3
108	Basic helix-loop-helix transcription factor	21		-	-	29.3
110	Aspartyl-phosphate phosphatase Spo0E	19		-	-	0.0
109	Transcription factor bHLH91-like	19		-	-	75.2
112	Hes family bHLH transcription factor 6	18		-	-	72.3
111	HLH transcription factor Hpa3	18		-	-	52.0
113	Transcription factor ILI1	17		-	-	22.6
114	N-acetyl-gamma-glutamyl-phosphate partial	17		-	-	75.5
116	Putative HLH transcription factor	14		-	-	73.8
115	Transcription factor bHLH113	14		-	-	36.5
119	Helix Loop Helix	13		-	-	11.9
118	Transcription factor bHLH10	13		-	-	70.1
117	Os01g0108400 protein	13		-	-	63.0
120	Spermatogenesis and oogenesis specific basic helix-loop-helix 1	13		-	-	13.6
121	Serine-rich protein TYE7	13		-	-	4.1
122	Retrograde regulation protein 1	13		-	-	25.9
124	transcription factor AP-4 isoform X3	12		-	-	5.4
123	Transcription factor bHLH113	12		-	-	52.9
128	Basic helix-loop-helix protein	11		-	-	42.4
132	CRE-HLH-2 protein	11		-	-	61.7
129	HLH DNA binding protein Penr2	11		-	-	11.1
131	Basic helix-loop-helix protein	11		-	-	3.8
125	Transcription factor EGL1	11		-	-	30.4
126	Protein WBSCR14 homolog	11		-	-	45.5
127	Helix-loop-helix protein 11	11		-	-	60.6
130	Unplaced genomic scaffold supercont1.11, whole genome shotgun sequence	11		-	-	16.2
133	BHLH transcription factor	10		-	-	51.1
134	Max-like protein X	10		-	-	41.1
135	Transcription factor MYC1	10		-	-	22.7
139	Clockwork orange, isoform B	9		-	-	0.0
136	CBN-MXL-2 protein	9		-	-	71.0
137	Transcription factor bHLH52	9		-	-	69.5
138	Basic helix-loop-helix BHLH	9		-	-	55.7
140	High-copy mep suppressor	9		-	-	11.1
142	Spermatogenesis and oogenesis specific basic helix-loop-helix 1	8		-	-	40.8
141	Basic helix-loop-helix BHLH	8		-	-	36.1
144	Uncharacterized protein	8		-	-	14.0
143	Rtg1p	8		-	-	13.1
145	Helix-loop-helix DNA-binding domain containing protein, expressed	8		-	-	67.2
147	Transcription factor AP-4 activating enhancer binding protein 4	7		-	-	7.5
146	Transcription factor bHLH162	7		-	-	70.1
149	Related to centromere binding factor 1	6		-	-	10.8
148	Basic helix-loop-helix BHLH	6		-	-	43.9
152	Nuclear pore complex protein NUP155	6		-	-	11.2
151	Transcription factor HES-1-B	6		-	-	41.6
150	Mesoderm posterior protein 1	6		-	-	14.1
156	Myogenic determination factor	5		-	-	41.4
153	Transcription factor bHLH167	5		-	-	29.6
155	Upstream stimulatory factor 2	5		-	-	23.2
154	Protein CBR-HLH-12	5		-	-	30.3
158	Sterol regulatory element Binding Protein	4		-	-	43.2
165	Transcription factor bHLH104	4		-	-	41.0
157	Uncharacterized protein	4		-	-	27.6
163	Transcriptional regulator CBF1	4		-	-	14.3
161	Predicted protein	4		-	-	6.8
164	Putative dna-binding protein inhibitor	4		-	-	12.8
160	Putative transcription factor bHLH041	4		-	-	13.6
159	Basic helix-loop-helix BHLH	4		-	-	0.0
162	Transcription factor BHLH148	4		-	-	0.0
170	Putative myc-like protein MYCLP1	3		-	-	12.2
181	Hairy enhancer of split	3		-	-	41.3
168	transcription factor protein	3		-	-	4.8
178	Uncharacterized protein	3		-	-	0.0
183	Transcription factor protein	3		-	-	30.4
179	Aryl hydrocarbon receptor nuclear translocator-like protein 2	3		-	-	0.0
177	Transcription factor	3		-	-	19.9
171	Basic helix-loop-helix family protein	3		-	-	7.3
176	Carbohydrate metabolism regulator TYE7	3		-	-	11.6
166	Transcription factor bHLH52	3		-	-	27.1
180	Transcription factor BPE	3		-	-	36.7
175	Inhibitor of DNA binding 1	3		-	-	0.0
174	YALI0D24167p	3		-	-	0.0
182	Basic helix-loop-helix	3		-	-	31.1
167	Helix-loop-helix protein 6	3		-	-	8.6
173	helix-loop-helix protein delilah	3		-	-	7.2
169	FI24210p1	3		-	-	5.6
172	Basic helix-loop-helix BHLH	3		-	-	1.3
191	Transcription factor UDT1	2		-	-	0.0
184	Uncharacterized protein	2		-	-	17.1
192	Transcription factor bHLH109	2		-	-	0.0
199	Uncharacterized protein	2		-	-	0.0
204	Neuronal stem cell leukemia 2-like protein	2		-	-	53.6
193	Uncharacterized protein	2		-	-	0.0
186	Transcriptional regulator of yeast form adherence 6	2		-	-	7.7
196	Uncharacterized protein	2		-	-	0.0
194	Max-like protein X	2		-	-	0.0
185	Uncharacterized protein	2		-	-	10.5
187	YALI0F05126p	2		-	-	0.0
198	Polyadenylate-binding protein	2		-	-	38.1
202	Transcription factor hes-1, putative	2		-	-	46.1
200	Hms1p	2		-	-	0.0
195	cDNA FLJ52911, highly similar to Max-like protein X	2		-	-	9.3
188	Transcription factor bHLH66	2		-	-	0.0
203	Uncharacterized protein	2		-	-	48.0
189	Uncharacterized protein	2		-	-	0.0
197	Predicted protein	2		-	-	29.6
201	Hms1p	2		-	-	0.0
190	Protein INO4, putative	2		-	-	5.9
232	MAX dimerization protein MLX	1		-	-	0.0
225	Uncharacterized protein	1		-	-	0.0
207	Transcription factor bHLH117	1		-	-	0.0
222	Transcription factor bHLH99	1		-	-	0.0
217	Uncharacterized protein	1		-	-	0.0
209	Uncharacterized protein	1		-	-	0.0
224	Uncharacterized protein	1		-	-	0.0
233	Uncharacterized protein	1		-	-	0.0
248	Predicted protein	1		-	-	0.0
236	Os03g0279500 protein	1		-	-	0.0
234	Helix Loop Helix	1		-	-	0.0
205	REF-1	1		-	-	0.0
227	Transcription factor bHLH14	1		-	-	0.0
214	MLX-interacting protein-like protein	1		-	-	0.0
226	Uncharacterized protein	1		-	-	0.0
244	Transcription factor bHLH62	1		-	-	0.0
237	Id-1	1		-	-	0.0
235	Transcription factor bHLH130	1		-	-	0.0
215	HER-2 protein	1		-	-	0.0
246	Uncharacterized protein	1		-	-	0.0
212	Transcription factor DYT1	1		-	-	0.0
229	Uncharacterized protein	1		-	-	0.0
247	Uncharacterized protein	1		-	-	0.0
210	Protein CBG18500	1		-	-	0.0
242	Uncharacterized protein	1		-	-	0.0
213	MAX-like-1 homolog	1		-	-	0.0
243	Uncharacterized protein	1		-	-	0.0
228	Transcription factor bHLH95	1		-	-	0.0
238	Uncharacterized protein	1		-	-	0.0
211	Uncharacterized protein	1		-	-	0.0
218	DNA binding protein	1		-	-	0.0
221	Uncharacterized protein ASH2	1		-	-	0.0
240	Uncharacterized protein	1		-	-	0.0
230	Extra macrochaetae-like protein	1		-	-	0.0
239	Predicted protein	1		-	-	0.0
219	Hairy-related 9	1		-	-	0.0
206	Uncharacterized protein	1		-	-	0.0
220	Achaete-scute family bHLH transcription factor 4	1		-	-	0.0
245	Transcription factor, putative	1		-	-	0.0
208	Predicted protein	1		-	-	0.0
241	Predicted protein	1		-	-	0.0
231	Uncharacterized bHLH domain-containing protein C3F10.12c	1		-	-	0.0
223	uncharacterized protein LOC100176581	1		-	-	0.0
216	BHLH transcription factor	1		-	-	0.0