The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 96: Basic helix-loop-helix (BHLH) DNA-binding superfam...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 F4KAJ5 (/ISS) Q0V7X4 (/ISS) Q0V7X4 (/ISS) Q700E3 (/ISS) Q9FT81 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q0V7X4 (/IPI) Q0V7X4 (/IPI) Q9FT81 (/IPI)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 Q9FT81 (/IDA)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 Q9FT81 (/IPI)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
4 F4KAJ5 (/TAS) Q0V7X4 (/TAS) Q0V7X4 (/TAS) Q700E3 (/TAS)
Response to iron ion GO:0010039
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
2 Q0V7X4 (/IMP) Q0V7X4 (/IMP)
Regulation of iron ion transport GO:0034756
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q0V7X4 (/IMP) Q0V7X4 (/IMP)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
2 Q0V7X4 (/IEP) Q0V7X4 (/IEP)
Cellular response to ethylene stimulus GO:0071369
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
2 Q0V7X4 (/IEP) Q0V7X4 (/IEP)
Cellular response to nitric oxide GO:0071732
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
2 Q0V7X4 (/IEP) Q0V7X4 (/IEP)
Jasmonic acid mediated signaling pathway GO:0009867
A series of molecular signals mediated by jasmonic acid.
1 Q9FT81 (/IMP)
Regulation of flavonoid biosynthetic process GO:0009962
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
1 Q9FT81 (/TAS)
Trichome differentiation GO:0010026
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.
1 Q9FT81 (/IMP)
Seed coat development GO:0010214
The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
1 Q9FT81 (/IMP)
Positive regulation of anthocyanin biosynthetic process GO:0031542
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
1 Q9FT81 (/IMP)
Seed development GO:0048316
The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
1 Q9FT81 (/IMP)
Regulation of proanthocyanidin biosynthetic process GO:2000029
Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.
1 Q9FT81 (/IEP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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