The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Transcription factor bHLH66

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
6 Q8S3D5 (/ISS) Q8S3D5 (/ISS) Q8S3D5 (/ISS) Q9LSQ3 (/ISS) Q9LSQ3 (/ISS) Q9ZUG9 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9ZUG9 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6 Q8S3D5 (/TAS) Q8S3D5 (/TAS) Q8S3D5 (/TAS) Q9LSQ3 (/TAS) Q9LSQ3 (/TAS) Q9ZUG9 (/TAS)
Root hair cell development GO:0080147
The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.
6 Q8S3D5 (/IMP) Q8S3D5 (/IMP) Q8S3D5 (/IMP) Q9LSQ3 (/IMP) Q9LSQ3 (/IMP) Q9ZUG9 (/IMP)
Pollen sperm cell differentiation GO:0048235
The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
4 Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q9ZUG9 (/IGI)
Root hair cell differentiation GO:0048765
The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
4 Q8S3D5 (/IMP) Q8S3D5 (/IMP) Q8S3D5 (/IMP) Q9ZUG9 (/IMP)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
4 Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q9ZUG9 (/IGI)
Microgametogenesis GO:0055046
The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.
4 Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q8S3D5 (/IGI) Q9ZUG9 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q9LSQ3 (/IDA) Q9LSQ3 (/IDA) Q9ZUG9 (/IDA)
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