The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 104: Transcription factor bHLH34

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
9 Q8W2F2 (/ISS) Q8W2F2 (/ISS) Q9FH37 (/ISS) Q9FH37 (/ISS) Q9FH37 (/ISS) Q9LT23 (/ISS) Q9LT23 (/ISS) Q9LTC7 (/ISS) Q9LTC7 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q9C682 (/IPI) Q9C682 (/IPI) Q9FH37 (/IPI) Q9FH37 (/IPI) Q9FH37 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
5 Q9FH37 (/IPI) Q9FH37 (/IPI) Q9FH37 (/IPI) Q9LT23 (/IPI) Q9LT23 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9LTC7 (/IDA) Q9LTC7 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
5 Q9FH37 (/TAS) Q9FH37 (/TAS) Q9FH37 (/TAS) Q9LTC7 (/TAS) Q9LTC7 (/TAS)
Glucosinolate metabolic process GO:0019760
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
3 Q9FH37 (/IMP) Q9FH37 (/IMP) Q9FH37 (/IMP)
Positive regulation of seed germination GO:0010030
Any process that activates or increase the rate of seed germination.
2 Q9LTC7 (/IGI) Q9LTC7 (/IGI)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 Q9LTC7 (/IMP) Q9LTC7 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q8W2F2 (/IDA) Q8W2F2 (/IDA) Q9C682 (/IDA) Q9C682 (/IDA) Q9FH37 (/IDA) Q9FH37 (/IDA) Q9FH37 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8W2F2 (/IDA) Q8W2F2 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q8W2F2 (/IDA) Q8W2F2 (/IDA)
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