CATH Superfamily 4.10.280.10

FunFam 10: Scleraxis bHLH transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 58 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	97	B5DFF0 (/IPI) O35437 (/IPI) O96004 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) (87 more)
E-box binding GO:0070888 Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.	64	B5DFF0 (/IDA) O35437 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (54 more)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	63	O96004 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) (53 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	62	O18374 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (52 more)
Activating transcription factor binding GO:0033613 Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.	60	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (50 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	43	O43680 (/ISM) O43680 (/ISM) O43680 (/ISM) O43680 (/ISM) O43680 (/ISM) O43680 (/ISM) O60682 (/ISM) O60682 (/ISM) O96004 (/ISM) P61296 (/ISM) (33 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	40	O43680 (/NAS) O43680 (/NAS) O43680 (/NAS) O43680 (/NAS) O43680 (/NAS) O43680 (/NAS) O60682 (/NAS) O60682 (/NAS) O96004 (/NAS) P61296 (/NAS) (30 more)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	36	O18374 (/IPI) Q0IGU7 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) (26 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	34	O35437 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (24 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	32	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (22 more)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	32	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (22 more)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	32	Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) Q61039 (/IPI) (22 more)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	30	P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) P61295 (/IMP) (20 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
AT DNA binding GO:0003680 Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
AT DNA binding GO:0003680 Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Activating transcription factor binding GO:0033613 Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.	30	P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) P61295 (/IPI) (20 more)
Activating transcription factor binding GO:0033613 Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
E-box binding GO:0070888 Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
E-box binding GO:0070888 Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.	22	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A7VJR9 (/ISS) A8E5T6 (/ISS) E1B9U0 (/ISS) E2R3U1 (/ISS) F7DSF8 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (12 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	18	O43680 (/ISA) O43680 (/ISA) O43680 (/ISA) O43680 (/ISA) O43680 (/ISA) O43680 (/ISA) O60682 (/ISA) O60682 (/ISA) O96004 (/ISA) Q12870 (/ISA) (8 more)
BHLH transcription factor binding GO:0043425 Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.	16	O43680 (/IPI) O43680 (/IPI) O43680 (/IPI) O43680 (/IPI) O43680 (/IPI) O43680 (/IPI) O96004 (/IPI) Q64124 (/IPI) Q64124 (/IPI) Q64279 (/IPI) (6 more)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	13	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) Q32PV5 (/ISS) Q498R2 (/ISS) Q5E9S3 (/ISS) Q5E9S3 (/ISS) Q5E9S3 (/ISS) Q6GNB7 (/ISS) (3 more)
Protein dimerization activity GO:0046983 The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.	10	A8E5T6 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) Q32PV5 (/ISS) Q6GNB7 (/ISS) Q6GNB7 (/ISS)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	9	O35437 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O88940 (/IDA) O96004 (/IDA)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	6	O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS)
BHLH transcription factor binding GO:0043425 Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.	5	O35437 (/ISO) Q64124 (/ISO) Q64124 (/ISO) Q64279 (/ISO) Q64279 (/ISO)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	5	Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	4	Q64124 (/IDA) Q64124 (/IDA) Q64279 (/IDA) Q64279 (/IDA)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	4	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.	3	O88940 (/IDA) Q64124 (/IDA) Q64124 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	3	O35437 (/ISO) Q64279 (/ISO) Q64279 (/ISO)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	3	O60682 (/TAS) O60682 (/TAS) Q12870 (/TAS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.	2	Q64279 (/ISO) Q64279 (/ISO)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	2	Q59E67 (/ISS) Q9VL05 (/ISS)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	2	Q64279 (/IDA) Q64279 (/IDA)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	2	O60682 (/TAS) O60682 (/TAS)
Enzyme binding GO:0019899 Interacting selectively and non-covalently with any enzyme.	2	Q64279 (/IPI) Q64279 (/IPI)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	2	Q64279 (/IPI) Q64279 (/IPI)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	2	Q64279 (/IDA) Q64279 (/IDA)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	2	Q64124 (/IDA) Q64124 (/IDA)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	2	Q64124 (/ISO) Q64124 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.	1	O96004 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	O96004 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	O88940 (/IMP)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	1	O96004 (/ISS)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	1	O96004 (/NAS)
Histone deacetylase binding GO:0042826 Interacting selectively and non-covalently with the enzyme histone deacetylase.	1	O35437 (/IPI)
Protein dimerization activity GO:0046983 The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.	1	O35437 (/IPI)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	1	O35437 (/IPI)

There are 271 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	68	B5DFF0 (/IDA) O35437 (/IDA) O96004 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (58 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	38	A7VJR9 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (28 more)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	35	P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) (25 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	35	B5DFF0 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (25 more)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	33	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (23 more)
Negative regulation of DNA-binding transcription factor activity GO:0043433 Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	33	O96004 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (23 more)
In utero embryonic development GO:0001701 The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.	32	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (22 more)
Heart looping GO:0001947 The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	32	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (22 more)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
Odontogenesis of dentin-containing tooth GO:0042475 The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	32	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (22 more)
Mesenchyme development GO:0060485 The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
Cartilage morphogenesis GO:0060536 The process in which the anatomical structures of cartilage are generated and organized.	32	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (22 more)
Determination of heart left/right asymmetry GO:0061371 Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.	32	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (22 more)
Heart morphogenesis GO:0003007 The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	31	P57102 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (21 more)
Cardiac right ventricle formation GO:0003219 The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.	31	O96004 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (21 more)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	31	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (21 more)
Suckling behavior GO:0001967 Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Regulation of secondary heart field cardioblast proliferation GO:0003266 Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Regulation of secondary heart field cardioblast proliferation GO:0003266 Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Apoptotic process involved in heart morphogenesis GO:0003278 Any apoptotic process that contributes to the shaping of the heart.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Noradrenergic neuron differentiation GO:0003357 The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.	30	P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) (20 more)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	30	P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) (20 more)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	30	P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) P61296 (/NAS) (20 more)
Adult heart development GO:0007512 The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.	30	P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) P61296 (/IEP) (20 more)
Adult heart development GO:0007512 The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Mesenchymal cell proliferation GO:0010463 The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of cardiac muscle hypertrophy GO:0010613 Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
Positive regulation of cardiac muscle hypertrophy GO:0010613 Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	30	P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) P61296 (/IGI) (20 more)
Positive regulation of cardiac muscle hypertrophy GO:0010613 Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	30	P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) (20 more)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667 Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667 Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Neural crest cell development GO:0014032 The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Regulation of tissue remodeling GO:0034103 Any process that modulates the frequency, rate, or extent of tissue remodeling.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
Regulation of tissue remodeling GO:0034103 Any process that modulates the frequency, rate, or extent of tissue remodeling.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Embryonic digit morphogenesis GO:0042733 The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Negative regulation of DNA binding GO:0043392 Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Tongue development GO:0043586 The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Negative regulation of osteoblast differentiation GO:0045668 Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Negative regulation of osteoblast differentiation GO:0045668 Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	30	Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) Q61039 (/IGI) (20 more)
Sympathetic nervous system development GO:0048485 The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Thymus development GO:0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Thymus development GO:0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Peripheral nervous system neuron development GO:0048935 The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.	30	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (20 more)
Roof of mouth development GO:0060021 The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Coronary artery morphogenesis GO:0060982 The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Visceral serous pericardium development GO:0061032 The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Cell proliferation involved in outflow tract morphogenesis GO:0061325 The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of ERK1 and ERK2 cascade GO:0070374 Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	30	P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) (20 more)
Positive regulation of ERK1 and ERK2 cascade GO:0070374 Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Cellular response to retinoic acid GO:0071300 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.	30	P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) (20 more)
Cellular response to organic cyclic compound GO:0071407 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	30	P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) P61295 (/IEP) (20 more)
Positive regulation of p38MAPK cascade GO:1900745 Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.	30	P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) P61296 (/IMP) (20 more)
Positive regulation of p38MAPK cascade GO:1900745 Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Primary palate development GO:1903929 The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of transcription regulatory region DNA binding GO:2000679 Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
Positive regulation of transcription regulatory region DNA binding GO:2000679 Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process GO:2000763 Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process GO:2000763 Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.	30	Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) Q61039 (/IMP) (20 more)
Positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.	30	P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (20 more)
Sertoli cell differentiation GO:0060008 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	29	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A7VJR9 (/ISS) A8E5T6 (/ISS) E1B9U0 (/ISS) E2R3U1 (/ISS) F7DSF8 (/ISS) O35437 (/ISS) O43680 (/ISS) O43680 (/ISS) (19 more)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	27	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A7VJR9 (/ISS) A8E5T6 (/ISS) E1B9U0 (/ISS) E2R3U1 (/ISS) F7DSF8 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (17 more)
Ureteric bud development GO:0001657 The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Branching involved in ureteric bud morphogenesis GO:0001658 The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Morphogenesis of a branching structure GO:0001763 The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Vasculature development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Sex determination GO:0007530 Any process that establishes and transmits the specification of sexual status of an individual organism.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Branchiomeric skeletal muscle development GO:0014707 The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Epithelial cell differentiation GO:0030855 The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Glomerulus development GO:0032835 The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Lung alveolus development GO:0048286 The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Embryonic digestive tract morphogenesis GO:0048557 The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O35437 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Reproductive structure development GO:0048608 The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Gland development GO:0048732 The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O35437 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Roof of mouth development GO:0060021 The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Lung morphogenesis GO:0060425 The process in which the anatomical structures of the lung are generated and organized.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Lung vasculature development GO:0060426 The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Bronchiole development GO:0060435 The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Respiratory system development GO:0060541 The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Metanephric mesenchymal cell differentiation GO:0072162 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Metanephric glomerular capillary formation GO:0072277 The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	19	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (9 more)
Spleen development GO:0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	17	A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) Q32PV5 (/ISS) Q498R2 (/ISS) (7 more)
Diaphragm development GO:0060539 The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.	17	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (7 more)
Negative regulation of androgen receptor signaling pathway GO:0060766 Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.	17	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) (7 more)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	13	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A8E5T6 (/ISS) E2R3U1 (/ISS) Q32PV5 (/ISS) Q498R2 (/ISS) Q5E9S3 (/ISS) Q5E9S3 (/ISS) Q5E9S3 (/ISS) Q6GNB7 (/ISS) (3 more)
Kidney development GO:0001822 The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.	10	A8E5T6 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) O43680 (/ISS) Q32PV5 (/ISS) Q6GNB7 (/ISS) Q6GNB7 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	9	O35437 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O88940 (/IDA) O96004 (/IDA)
Mesoderm formation GO:0001707 The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Tissue homeostasis GO:0001894 A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Endochondral ossification GO:0001958 Replacement ossification wherein bone tissue replaces cartilage.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Chondrocyte differentiation GO:0002062 The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Heart valve morphogenesis GO:0003179 The process in which the structure of a heart valve is generated and organized.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Heart valve formation GO:0003188 The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Transcription, DNA-templated GO:0006351 The cellular synthesis of RNA on a template of DNA.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Collagen fibril organization GO:0030199 Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
BMP signaling pathway GO:0030509 A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Positive regulation of collagen biosynthetic process GO:0032967 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Tendon development GO:0035989 The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Tendon formation GO:0035992 The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Deltoid tuberosity development GO:0035993 The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Regulation of cartilage development GO:0061035 Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Positive regulation of cartilage development GO:0061036 Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Positive regulation of gastrulation GO:2000543 Any process that activates or increases the frequency, rate or extent of gastrulation.	9	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Cell differentiation GO:0030154 The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	8	A7VJR9 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Tendon cell differentiation GO:0035990 The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.	8	A7VJR9 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS) Q7RTU7 (/ISS)
Transcription, DNA-templated GO:0006351 The cellular synthesis of RNA on a template of DNA.	7	Q64124 (/IDA) Q64124 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA) Q7RTU7 (/IDA)
Mesoderm formation GO:0001707 The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	4	Q64124 (/IMP) Q64124 (/IMP) Q64279 (/IMP) Q64279 (/IMP)
Cellular response to BMP stimulus GO:0071773 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.	4	B5DFF0 (/IEP) P59101 (/IEP) Q64124 (/IEP) Q64124 (/IEP)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	3	O35437 (/ISO) Q64279 (/ISO) Q64279 (/ISO)
Embryonic heart tube formation GO:0003144 The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	3	P57102 (/IMP) Q64279 (/IMP) Q64279 (/IMP)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	3	B5DFF0 (/IDA) Q64124 (/IDA) Q64124 (/IDA)
Embryonic heart tube development GO:0035050 The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.	3	Q64279 (/IMP) Q64279 (/IMP) Q9VL05 (/IMP)
Decidualization GO:0046697 The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.	3	Q7RTU1 (/IMP) Q7RTU1 (/IMP) Q7RTU1 (/IMP)
Ventricular cardiac muscle tissue morphogenesis GO:0055010 The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.	3	O96004 (/IMP) Q64279 (/IMP) Q64279 (/IMP)
Sclerotome development GO:0061056 The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	3	P59101 (/IEP) Q64124 (/IEP) Q64124 (/IEP)
Cellular response to transforming growth factor beta stimulus GO:0071560 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.	3	B5DFF0 (/IEP) Q64124 (/IEP) Q64124 (/IEP)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	Q64279 (/IGI) Q64279 (/IGI)
Angiogenesis GO:0001525 Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.	2	Q64279 (/IMP) Q64279 (/IMP)
Cell fate determination GO:0001709 A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	2	Q64279 (/NAS) Q64279 (/NAS)
Tissue homeostasis GO:0001894 A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.	2	Q64124 (/IMP) Q64124 (/IMP)
Endochondral ossification GO:0001958 Replacement ossification wherein bone tissue replaces cartilage.	2	Q64124 (/IMP) Q64124 (/IMP)
Chondrocyte differentiation GO:0002062 The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.	2	Q64124 (/IMP) Q64124 (/IMP)
Heart morphogenesis GO:0003007 The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	2	Q64279 (/NAS) Q64279 (/NAS)
Heart morphogenesis GO:0003007 The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	2	Q64279 (/TAS) Q64279 (/TAS)
Heart valve morphogenesis GO:0003179 The process in which the structure of a heart valve is generated and organized.	2	Q64124 (/IMP) Q64124 (/IMP)
Heart valve formation GO:0003188 The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	2	Q64124 (/IMP) Q64124 (/IMP)
Cardiac left ventricle formation GO:0003218 The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.	2	Q64279 (/ISO) Q64279 (/ISO)
Cardiac right ventricle formation GO:0003219 The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.	2	Q64279 (/ISO) Q64279 (/ISO)
Transcription, DNA-templated GO:0006351 The cellular synthesis of RNA on a template of DNA.	2	Q64124 (/ISO) Q64124 (/ISO)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	2	Q59E67 (/ISS) Q9VL05 (/ISS)
Transcription by RNA polymerase II GO:0006366 The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	2	Q64279 (/ISO) Q64279 (/ISO)
Transcription by RNA polymerase II GO:0006366 The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	2	O60682 (/TAS) O60682 (/TAS)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	2	Q64279 (/IMP) Q64279 (/IMP)
Skeletal muscle tissue development GO:0007519 The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.	2	A0A2R8QBT6 (/IGI) Q32PV5 (/IGI)
Skeletal muscle tissue development GO:0007519 The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.	2	A0A2R8QBT6 (/IMP) Q32PV5 (/IMP)
Visceral muscle development GO:0007522 The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.	2	O18374 (/IMP) Q0IGU7 (/IMP)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	2	Q64124 (/IMP) Q64124 (/IMP)
Branchiomeric skeletal muscle development GO:0014707 The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.	2	O35437 (/IGI) O88940 (/IGI)
Cell differentiation GO:0030154 The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	2	Q64279 (/IGI) Q64279 (/IGI)
Cell differentiation GO:0030154 The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	2	Q64124 (/IMP) Q64124 (/IMP)
Collagen fibril organization GO:0030199 Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.	2	Q64124 (/IMP) Q64124 (/IMP)
BMP signaling pathway GO:0030509 A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	2	Q64124 (/IMP) Q64124 (/IMP)
Positive regulation of collagen biosynthetic process GO:0032967 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	2	Q64124 (/IDA) Q64124 (/IDA)
Positive regulation of collagen biosynthetic process GO:0032967 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	2	Q64124 (/IMP) Q64124 (/IMP)
Skeletal muscle cell differentiation GO:0035914 The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.	2	Q64124 (/IMP) Q64124 (/IMP)
Tendon development GO:0035989 The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.	2	Q64124 (/IMP) Q64124 (/IMP)
Tendon cell differentiation GO:0035990 The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.	2	Q64124 (/IMP) Q64124 (/IMP)
Tendon formation GO:0035992 The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.	2	Q64124 (/IMP) Q64124 (/IMP)
Deltoid tuberosity development GO:0035993 The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.	2	Q64124 (/IMP) Q64124 (/IMP)
Negative regulation of DNA-binding transcription factor activity GO:0043433 Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	2	Q64279 (/ISO) Q64279 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	2	Q64124 (/IMP) Q64124 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	2	Q64279 (/ISO) Q64279 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	2	O18374 (/IMP) Q0IGU7 (/IMP)
Embryonic skeletal system development GO:0048706 The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.	2	Q64124 (/IEP) Q64124 (/IEP)
Cartilage development GO:0051216 The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	2	Q64124 (/NAS) Q64124 (/NAS)
Ventricular cardiac muscle tissue morphogenesis GO:0055010 The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.	2	Q64279 (/ISO) Q64279 (/ISO)
Roof of mouth development GO:0060021 The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.	2	O35437 (/IGI) O88940 (/IGI)
Face morphogenesis GO:0060325 The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.	2	Q64124 (/IEP) Q64124 (/IEP)
Cardiac septum morphogenesis GO:0060411 The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	2	Q64279 (/ISO) Q64279 (/ISO)
Diaphragm development GO:0060539 The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.	2	O35437 (/IGI) O88940 (/IGI)
Trophoblast giant cell differentiation GO:0060707 The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.	2	Q64279 (/IDA) Q64279 (/IDA)
Trophoblast giant cell differentiation GO:0060707 The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.	2	Q64279 (/IMP) Q64279 (/IMP)
Regulation of cartilage development GO:0061035 Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	2	Q64124 (/IMP) Q64124 (/IMP)
Positive regulation of cartilage development GO:0061036 Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	2	Q64124 (/IMP) Q64124 (/IMP)
Cellular response to mechanical stimulus GO:0071260 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	2	Q64124 (/IEP) Q64124 (/IEP)
Glomus development GO:0072013 The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.	2	Q6GNB7 (/IMP) Q6GNB7 (/IMP)
Negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding GO:1903026 Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	2	Q64279 (/ISO) Q64279 (/ISO)
Positive regulation of gastrulation GO:2000543 Any process that activates or increases the frequency, rate or extent of gastrulation.	2	Q64124 (/IMP) Q64124 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	O88940 (/IMP)
Angiogenesis GO:0001525 Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.	1	O96004 (/ISS)
Ureteric bud development GO:0001657 The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.	1	O35437 (/IMP)
Branching involved in ureteric bud morphogenesis GO:0001658 The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	1	O35437 (/IMP)
Somitogenesis GO:0001756 The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	1	Q60756 (/IMP)
Morphogenesis of a branching structure GO:0001763 The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.	1	O35437 (/IMP)
Kidney development GO:0001822 The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.	1	O35437 (/IMP)
Blastocyst development GO:0001824 The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.	1	O96004 (/IEP)
Trophectodermal cell differentiation GO:0001829 The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.	1	O96004 (/IEP)
Vasculature development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	1	O35437 (/IMP)
Heart looping GO:0001947 The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	1	P57102 (/IGI)
Heart looping GO:0001947 The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	1	O96004 (/ISS)
Heart morphogenesis GO:0003007 The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	1	P57102 (/IGI)
Respiratory system process GO:0003016 A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.	1	Q60756 (/IMP)
Cardiogenic plate morphogenesis GO:0003142 The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.	1	P57102 (/IMP)
Cardiac left ventricle formation GO:0003218 The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.	1	O96004 (/IMP)
Proepicardium development GO:0003342 The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.	1	P57102 (/IMP)
Noradrenergic neuron differentiation GO:0003357 The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.	1	P57102 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357 Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	Q12870 (/TAS)
Transcription by RNA polymerase II GO:0006366 The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	1	O96004 (/IDA)
Mesoderm development GO:0007498 The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.	1	Q12870 (/TAS)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	1	O96004 (/ISS)
Larval heart development GO:0007508 The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.	1	Q9VL05 (/IMP)
Muscle organ development GO:0007517 The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.	1	Q60756 (/IMP)
Sex determination GO:0007530 Any process that establishes and transmits the specification of sexual status of an individual organism.	1	O35437 (/IMP)
Sex differentiation GO:0007548 The establishment of the sex of an organism by physical differentiation.	1	O35437 (/IMP)
Animal organ morphogenesis GO:0009887 Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	1	O35437 (/IMP)
Polarity specification of anterior/posterior axis GO:0009949 Any process resulting in the establishment of polarity along the anterior/posterior axis.	1	Q90690 (/IMP)
Anterior/posterior pattern specification GO:0009952 The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	1	Q60756 (/IMP)
Cardioblast differentiation GO:0010002 The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	1	P57102 (/IMP)
Regulation of gene expression GO:0010468 Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	Q60756 (/IMP)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	B5DFF0 (/IDA)
Branchiomeric skeletal muscle development GO:0014707 The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.	1	Q32PV5 (/IMP)
Hemopoiesis GO:0030097 The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.	1	Q9VL05 (/IMP)
Epithelial cell differentiation GO:0030855 The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.	1	O35437 (/IMP)
Polarized epithelial cell differentiation GO:0030859 The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.	1	P57102 (/IMP)
Thyroid gland development GO:0030878 The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.	1	P57102 (/IMP)
Regulation of histone deacetylation GO:0031063 Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.	1	O35437 (/IC)
Glomerulus development GO:0032835 The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.	1	O35437 (/IMP)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968 Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	1	Q9VL05 (/IDA)
Embryonic heart tube development GO:0035050 The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.	1	O96004 (/ISS)
Cardiocyte differentiation GO:0035051 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.	1	P57102 (/IMP)
Embryonic pectoral fin morphogenesis GO:0035118 The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	1	P57102 (/IMP)
Tendon development GO:0035989 The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.	1	P59101 (/IEP)
Tendon cell differentiation GO:0035990 The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.	1	B5DFF0 (/IEP)
Post-anal tail morphogenesis GO:0036342 The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.	1	Q60756 (/IMP)
Eating behavior GO:0042755 The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.	1	Q60756 (/IMP)
Ear development GO:0043583 The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.	1	Q60756 (/IMP)
Skin development GO:0043588 The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.	1	Q60756 (/IMP)
Cellular response to fibroblast growth factor stimulus GO:0044344 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.	1	P59101 (/IEP)
Establishment of epithelial cell apical/basal polarity GO:0045198 The specification and formation of the apicobasal polarity of an epithelial cell.	1	Q60756 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	1	O96004 (/IDA)
Decidualization GO:0046697 The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.	1	Q9JLR5 (/ISO)
Lung alveolus development GO:0048286 The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.	1	O35437 (/IMP)
Paraxial mesoderm development GO:0048339 The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.	1	Q60756 (/IMP)
Sympathetic nervous system development GO:0048485 The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.	1	P57102 (/IMP)
Spleen development GO:0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	1	O35437 (/IMP)
Embryonic digestive tract morphogenesis GO:0048557 The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.	1	Q498R2 (/IMP)
Embryonic digestive tract morphogenesis GO:0048557 The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.	1	O35437 (/ISO)
Reproductive structure development GO:0048608 The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.	1	O35437 (/IMP)
Muscle organ morphogenesis GO:0048644 The process in which the anatomical structures of muscle are generated and organized.	1	Q60756 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703 The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.	1	P57102 (/IGI)
Embryonic viscerocranium morphogenesis GO:0048703 The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.	1	P57102 (/IMP)
Skeletal system morphogenesis GO:0048705 The process in which the anatomical structures of the skeleton are generated and organized.	1	Q60756 (/IMP)
Gland development GO:0048732 The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.	1	Q498R2 (/IMP)
Gland development GO:0048732 The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.	1	O35437 (/ISO)
Dendrite morphogenesis GO:0048813 The process in which the anatomical structures of a dendrite are generated and organized.	1	Q9VL05 (/IMP)
Neuromuscular process controlling posture GO:0050884 Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.	1	Q60756 (/IMP)
Cardiac muscle cell differentiation GO:0055007 The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	1	P57102 (/IMP)
Sertoli cell differentiation GO:0060008 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	1	Q498R2 (/IDA)
Sertoli cell differentiation GO:0060008 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	1	B5DFF0 (/IMP)
Sertoli cell differentiation GO:0060008 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	1	O35437 (/ISO)
Sertoli cell development GO:0060009 The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.	1	B5DFF0 (/IEP)
Heart contraction GO:0060047 The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.	1	P57102 (/IMP)
Limb bud formation GO:0060174 The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.	1	Q90690 (/IMP)
Mesenchymal to epithelial transition GO:0060231 A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.	1	Q60756 (/IMP)
Cardiac septum morphogenesis GO:0060411 The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	1	O96004 (/IMP)
Lung morphogenesis GO:0060425 The process in which the anatomical structures of the lung are generated and organized.	1	O35437 (/IMP)
Lung vasculature development GO:0060426 The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.	1	O35437 (/IMP)
Bronchiole development GO:0060435 The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	1	O35437 (/IMP)
Respiratory system development GO:0060541 The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.	1	O35437 (/IMP)
Negative regulation of androgen receptor signaling pathway GO:0060766 Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.	1	O35437 (/IDA)
Artery development GO:0060840 The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.	1	Q32PV5 (/IGI)
Cellular response to cAMP GO:0071320 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.	1	B5DFF0 (/IEP)
Cellular response to follicle-stimulating hormone stimulus GO:0071372 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.	1	B5DFF0 (/IEP)
Determination of intestine left/right asymmetry GO:0071908 Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.	1	P57102 (/IMP)
Metanephric mesenchymal cell differentiation GO:0072162 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.	1	O35437 (/IMP)
Metanephric glomerular capillary formation GO:0072277 The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	1	O35437 (/IMP)
Negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding GO:1903026 Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	1	O96004 (/IDA)
Regulation of extracellular matrix organization GO:1903053 Any process that modulates the frequency, rate or extent of extracellular matrix organization.	1	Q60756 (/IMP)
Cellular response to leukemia inhibitory factor GO:1990830 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.	1	O88940 (/IEP)

There are 21 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	80	O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O43680 (/IDA) O88940 (/IDA) O96004 (/IDA) P61295 (/IDA) P61295 (/IDA) (70 more)
Transcription factor complex GO:0005667 A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	37	Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) Q61039 (/IDA) (27 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	35	O35437 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (25 more)
Transcription factor complex GO:0005667 A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	34	A7VJR9 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) F7DSF8 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) P61296 (/ISS) (24 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	33	O35437 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) P61295 (/IC) (23 more)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	30	Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) Q61039 (/TAS) (20 more)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	30	P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) P61296 (/IDA) (20 more)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	30	Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) Q61039 (/ISO) (20 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	18	A0A287B8H6 (/ISS) A0A287B8H6 (/ISS) A7VJR9 (/ISS) A8E5T6 (/ISS) B5DFF0 (/ISS) E1B9U0 (/ISS) E2R3U1 (/ISS) F7DSF8 (/ISS) O18374 (/ISS) Q0IGU7 (/ISS) (8 more)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	4	O60682 (/IDA) O60682 (/IDA) Q64279 (/IDA) Q64279 (/IDA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	2	O60682 (/TAS) O60682 (/TAS)
Transcription factor complex GO:0005667 A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	2	Q64124 (/ISO) Q64124 (/ISO)
Nucleolus GO:0005730 A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	2	Q64279 (/IDA) Q64279 (/IDA)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	2	Q64279 (/ISO) Q64279 (/ISO)
RNA polymerase II transcription factor complex GO:0090575 A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.	2	O96004 (/IDA) Q60756 (/IDA)
RNA polymerase II transcription factor complex GO:0090575 A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.	2	Q64279 (/ISO) Q64279 (/ISO)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	Q9VL05 (/HDA)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	1	O88940 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	O96004 (/IDA)

CATH Superfamily 4.10.280.10

Helix-loop-helix DNA-binding domain

Functional Families

FunFam 10: Scleraxis bHLH transcription factor

There are 58 GO terms relating to "molecular function"

There are 271 GO terms relating to "biological process"

There are 21 GO terms relating to "cellular component"