The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: ADP-sugar pyrophosphatase isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 23 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ADP-ribose diphosphatase activity GO:0047631
Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
5 Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA) Q9UKK9 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
ADP-sugar diphosphatase activity GO:0019144
Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9UKK9 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
8-oxo-dGDP phosphatase activity GO:0044715
Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
ADP-ribose diphosphatase activity GO:0047631
Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
ADP-ribose diphosphatase activity GO:0047631
Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
2 Q9JKX6 (/ISO) Q9P791 (/ISO)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9UKK9 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9JKX6 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9UKK9 (/IPI)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
1 Q9UKK9 (/IDA)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
1 Q9JKX6 (/ISO)
Nucleoside-diphosphatase activity GO:0017110
Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
1 Q9JKX6 (/IDA)
ADP-sugar diphosphatase activity GO:0019144
Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.
1 Q9UKK9 (/IDA)
ADP-sugar diphosphatase activity GO:0019144
Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.
1 Q9JKX6 (/ISO)
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
1 Q9JKX6 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9UKK9 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9JKX6 (/ISO)
8-oxo-dGDP phosphatase activity GO:0044715
Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
1 Q9UKK9 (/IDA)
8-oxo-dGDP phosphatase activity GO:0044715
Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
1 Q9JKX6 (/ISO)
ADP-ribose diphosphatase activity GO:0047631
Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
1 Q9UKK9 (/EXP)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
Ribonucleoside diphosphate catabolic process GO:0009191
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
D-ribose catabolic process GO:0019303
The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
Ribose phosphate metabolic process GO:0019693
The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.
4 Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 Q9JKX6 (/IDA)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q9UKK9 (/IDA)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q9JKX6 (/ISO)
Nucleotide metabolic process GO:0009117
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
1 Q9UKK9 (/NAS)
Ribonucleoside diphosphate catabolic process GO:0009191
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
1 Q9P791 (/IC)
Ribonucleoside diphosphate catabolic process GO:0009191
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
1 Q9UKK9 (/IDA)
Ribonucleoside diphosphate catabolic process GO:0009191
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
1 Q9JKX6 (/ISO)
Ribonucleoside diphosphate catabolic process GO:0009191
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
1 Q9UKK9 (/TAS)
D-ribose catabolic process GO:0019303
The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
1 Q9UKK9 (/IDA)
D-ribose catabolic process GO:0019303
The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
1 Q9JKX6 (/ISO)
D-ribose catabolic process GO:0019303
The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
1 Q9UKK9 (/NAS)
Nucleobase-containing small molecule catabolic process GO:0034656
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
1 Q9UKK9 (/TAS)
ATP generation from poly-ADP-D-ribose GO:1990966
The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
1 Q9UKK9 (/IDA)
ATP generation from poly-ADP-D-ribose GO:1990966
The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
1 Q9JKX6 (/ISO)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA) Q9P791 (/HDA) Q9UKK9 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q5RCY2 (/ISS) Q5RCY2 (/ISS) Q6AY63 (/ISS) Q9JKX6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA) Q01976 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA) Q01976 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UKK9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JKX6 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9P791 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 C8VDH4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UKK9 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q9UKK9 (/HDA)
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