The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cysteine proteinases
".
FunFam 39: Cysteine proteinase 2, putative
There are 3 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Histolysain.
[EC: 3.4.22.35]
Hydrolysis of proteins, including basement membrane collagen and azocasein. Preferential cleavage: Arg-Arg-|-Xaa in small molecule substrates including Z-Arg-Arg-|-NHMec.
|
25 |
M2RGE9
M2RGE9
M2RGE9
M2RGE9
M2RGE9
M3S7G8
M3S7G8
M3S7G8
M3S7G8
M3S7G8 (15 more...) |
|
Cathepsin H.
[EC: 3.4.22.16]
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase.
|
14 |
A0A384KV08
A0A384KV08
A0A384KV08
B9DG56
B9DG56
B9DG56
M0VNM8
M0VNM8
P05167
P05167 (4 more...) |
|
Cathepsin L.
[EC: 3.4.22.15]
Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.
|
1 | O45734 |
