The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cysteine proteinases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 38: Calpain-type cysteine protease DEK1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
2 Q8RVL1 (/IMP) Q8RVL2 (/IMP)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 F4I0A4 (/IDA)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 Q6ZFZ4 (/ISS)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 F4I0A4 (/IMP) Q8RVL2 (/IMP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Regulation of meristem structural organization GO:0009934
Any process that modulates the frequency, rate or extent of meristem organization.
2 Q6ZFZ4 (/IMP) Q8RVL2 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Plant epidermal cell fate specification GO:0090628
The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Regulation of adaxial/abaxial pattern formation GO:2000011
Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.
2 Q8RVL1 (/ISS) Q8RVL2 (/ISS)
Regulation of endosperm development GO:2000014
Any process that modulates the frequency, rate or extent of endosperm development.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Regulation of leaf development GO:2000024
Any process that modulates the frequency, rate or extent of leaf development.
2 Q6ZFZ4 (/IMP) Q8RVL2 (/IMP)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q8RVL2 (/IMP)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
1 F4I0A4 (/IMP)
Regulation of meristem structural organization GO:0009934
Any process that modulates the frequency, rate or extent of meristem organization.
1 Q8RVL1 (/ISS)
Positive regulation of DNA endoreduplication GO:0032877
Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
1 Q8RVL2 (/IMP)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1 F4I0A4 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q8RVL2 (/IMP)
Sepal giant cell differentiation GO:0090392
The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.
1 Q8RVL2 (/IMP)
Plant epidermal cell fate specification GO:0090628
The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
1 Q8RVL2 (/IMP)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 Q8RVL2 (/IDA)
Regulation of adaxial/abaxial pattern formation GO:2000011
Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.
1 Q6ZFZ4 (/IMP)
Regulation of endosperm development GO:2000014
Any process that modulates the frequency, rate or extent of endosperm development.
1 Q8RVL2 (/IMP)
Regulation of leaf development GO:2000024
Any process that modulates the frequency, rate or extent of leaf development.
1 Q8RVL1 (/ISS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 F4I0A4 (/IDA) Q8RVL2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q6ZFZ4 (/ISS) Q8RVL1 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8RVL1 (/IDA) Q8RVL2 (/IDA)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
2 Q8RVL1 (/IDA) Q8RVL2 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 F4I0A4 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q8RVL2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 F4I0A4 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6ZFZ4 (/ISS)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
1 Q6ZFZ4 (/ISS)
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