The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cysteine proteinases
".
FunFam 14: Ubiquitin carboxyl-terminal hydrolase 34
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
6 | A0A0B4KHF3 (/ISS) A0A0B4KI06 (/ISS) A0A0B4LIK5 (/ISS) Q6ZQ93 (/ISS) Q8IMW2 (/ISS) Q9VC56 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q70CQ2 (/IPI) Q9VC56 (/IPI) |
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | Q70CQ2 (/IMP) |
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | Q6ZQ93 (/ISO) |
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | Q6ZQ93 (/ISS) |
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q70CQ2 (/IDA) |
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q6ZQ93 (/ISO) |
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q70CQ2 (/IDA) |
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q6ZQ93 (/ISO) |
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q6ZQ93 (/ISS) |
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q70CQ2 (/TAS) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
5 | A0A0B4KHF3 (/ISS) A0A0B4KI06 (/ISS) A0A0B4LIK5 (/ISS) Q8IMW2 (/ISS) Q9VC56 (/ISS) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
5 | A0A0B4KHF3 (/IGI) A0A0B4KI06 (/IGI) A0A0B4LIK5 (/IGI) Q8IMW2 (/IGI) Q9VC56 (/IGI) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Regulation of gene silencing GO:0060968
Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
|
5 | A0A0B4KHF3 (/IMP) A0A0B4KI06 (/IMP) A0A0B4LIK5 (/IMP) Q8IMW2 (/IMP) Q9VC56 (/IMP) |
Negative regulation of antimicrobial peptide production GO:0002785
Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
|
1 | Q9VC56 (/IMP) |
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
1 | Q70CQ2 (/TAS) |
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q70CQ2 (/IDA) |
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q6ZQ93 (/ISO) |
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q70CQ2 (/TAS) |
Negative regulation of Toll signaling pathway GO:0045751
Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.
|
1 | Q9VC56 (/IMP) |
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
|
1 | Q9VC56 (/IMP) |
Negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060
Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
|
1 | Q9VC56 (/IMP) |
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q70CQ2 (/IDA) |
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q6ZQ93 (/ISO) |
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q6ZQ93 (/ISS) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q70CQ2 (/IDA) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q6ZQ93 (/ISO) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q6ZQ93 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | A0A0B4KHF3 (/IDA) A0A0B4KI06 (/IDA) A0A0B4LIK5 (/IDA) Q8IMW2 (/IDA) Q9VC56 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q70CQ2 (/TAS) |