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CATH Superfamily 3.60.110.10

Carbon-nitrogen hydrolase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Carbon-nitrogen hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Bifunctional nitrilase/nitrile hydratase NIT4B

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nitrilase. [EC: 3.5.5.1]
A nitrile + 2 H(2)O = a carboxylate + NH(3).
  • Acts on a wide range of aromatic nitriles including (indol-3- yl)acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amides (cf. EC 4.2.1.84).
 35 A0A0D3F7Z9 A0A0D3F7Z9 A0A0D3F7Z9 A0A0E0NI73 A0A0E0NI73 A0A0E0NI73 A0A178U938 A0A178U938 A0A178VEJ6 A0A178VEJ6
(25 more...)
Cyanoalanine nitrilase. [EC: 3.5.5.4]
3-cyano-L-alanine + 2 H(2)O = L-aspartate + NH(3).
  • L-asparagine is formed as an intermediate.
  • Cf. EC 4.2.1.65 and EC 3.5.1.1.
 15 A0A0D3F7Z9 A0A0D3F7Z9 A0A0D3F7Z9 A0A0E0NI73 A0A0E0NI73 A0A0E0NI73 A0A178U938 A0A178U938 P46011 P46011
(5 more...)
3-cyanoalanine hydratase. [EC: 4.2.1.65]
L-asparagine = 3-cyanoalanine + H(2)O.
    		 6 A0A178U938 A0A178U938 P46011 P46011 Q3LRV4 Q5QGZ8