The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldehyde Dehydrogenase; Chain A, domain 1
".
FunFam 22: Aldehyde dehydrogenase A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
8 | P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) P25553 (/ISS) |
|
Lactaldehyde dehydrogenase activity GO:0008911
Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.
|
8 | P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
8 | P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) |
|
Glycolaldehyde dehydrogenase activity GO:0050569
Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH.
|
8 | P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q6L285 (/IDA) Q9HK01 (/IDA) |
|
Glyceraldehyde dehydrogenase (NADP) activity GO:0043796
Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.
|
2 | Q6L285 (/IDA) Q9HK01 (/IDA) |
|
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
|
1 | H8ZPX2 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
9 | P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) Q9HK01 (/IDA) |
|
Rhamnose catabolic process GO:0019301
The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
|
8 | P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) P25553 (/IMP) |
|
L-fucose catabolic process GO:0042355
The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
|
8 | P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) P25553 (/IEP) |
|
Entner-Doudoroff pathway through 6-phosphogluconate GO:0009255
A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.
|
2 | Q6L285 (/IDA) Q9HK01 (/IDA) |
|
Nicotine catabolic process GO:0019608
The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
|
1 | H8ZPX2 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | Q6L285 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) P25553 (/IDA) |
