The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 57: 2-oxoisovalerate dehydrogenase subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alpha-ketoacid dehydrogenase activity GO:0003826
Catalysis of an oxidation-reduction (redox) reaction involving an alpha-ketoacid.
8 Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS)
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
1 Q38CH4 (/ISM)
2-oxoisovalerate dehydrogenase (acylating) activity GO:0047101
Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.
1 Q38CH4 (/ISA)

There are 0 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0005947
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
8 Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS) Q8IEJ6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q38CH4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QC52 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q38CH4 (/ISA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q38CH4 (/RCA)