The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: 1-deoxy-D-xylulose-5-phosphate synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1-deoxy-D-xylulose-5-phosphate synthase activity GO:0008661
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
30 P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA)
(20 more)
Thiamine pyrophosphate binding GO:0030976
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
18 P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA)
(8 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
10 P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
10 P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA)
Thiamine binding GO:0030975
Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
10 P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA)
1-deoxy-D-xylulose-5-phosphate synthase activity GO:0008661
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
8 Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q38854 (/IPI) Q38854 (/IPI)
1-deoxy-D-xylulose-5-phosphate synthase activity GO:0008661
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
2 F4IXL8 (/TAS) Q9LFL9 (/TAS)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0019288
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
28 P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP)
(18 more)
Ubiquinone biosynthetic process GO:0006744
The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
18 P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA)
(8 more)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
18 P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP)
(8 more)
Pyridoxine biosynthetic process GO:0008615
The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
18 P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA)
(8 more)
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
18 P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP) P77488 (/IMP)
(8 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10 P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP) P9WNS3 (/IMP)
Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0019288
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
10 P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA) P9WNS3 (/IDA)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
8 Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS)
Pyridoxine biosynthetic process GO:0008615
The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
8 Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS)
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
8 Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS) Q9KTL3 (/ISS)
Chlorophyll biosynthetic process GO:0015995
The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
2 Q38854 (/IMP) Q38854 (/IMP)
Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0019288
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
2 Q38854 (/TAS) Q38854 (/TAS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
18 P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA) P77488 (/IDA)
(8 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O50408 (/HDA) O50408 (/HDA) O50408 (/HDA) O50408 (/HDA) O50408 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 O50408 (/HDA) O50408 (/HDA) O50408 (/HDA) O50408 (/HDA) O50408 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 F4IXL8 (/IDA) Q38854 (/IDA) Q38854 (/IDA)
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