The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: Gamma-glutamyl peptidase 5

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glucosinolate gamma-glutamyl hydrolase. [EC: 3.4.19.16]
(1) An S-((1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl)-L- glutathione + H(2)O = an S-((1E)-1-(hydroxyimino)-omega- (methylsulfanyl)alkyl)-L-cysteinylglycine + L-glutamate. (2) (E)-1-(glutathion-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(2)O = (E)-1-(glycylcystein-S-yl)-2-(1H-indol-3-yl)acetohydroximate + L-glutamate. (3) 2-(glutathion-S-yl)-2-(1H-indol-3-yl)acetonitrile + H(2)O = 2-(glycylcystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + L-glutamate. (4) (Z)-1-(glutathion-S-yl)-2-phenylacetohydroximate + H(2)O = (Z)-1- (glycylcystein-S-yl)-2-phenylacetohydroximate + L-glutamate.
  • This enzyme, characterized from the plant Arabidopsis thaliana, participates in the biosynthesis of the plant defense compounds glucosinolates and camalexin.
  • It is the only known plant enzyme capable of hydrolyzing the gamma- glutamyl residue of glutathione in the cytosol.
9 A0A178V143 A0A178V143 A0A178V361 A0A178V361 Q9M0A5 Q9M0A5 Q9M0A6 Q9M0A7 Q9M0A7
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