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CATH Superfamily 3.40.50.880

Class I glutamine amidotransferase (GATase) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 31: Multifunctional tryptophan biosynthesis protein

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Anthranilate synthase. [EC: 4.1.3.27]
Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20 and EC 5.3.1.24).
  • The native enzyme in the complex with uses either glutamine or (less efficiently) NH(3).
  • The enzyme separated from the complex uses NH(3) only.
 74 A0A0B0EAI5 A0A0B0EAI5 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1
(64 more...)
Indole-3-glycerol-phosphate synthase. [EC: 4.1.1.48]
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C- (3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).
 73 A0A0B0EAI5 A0A0B0EAI5 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1 A0A0L8VML1
(63 more...)
Phosphoribosylanthranilate isomerase. [EC: 5.3.1.24]
N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1- deoxy-D-ribulose 5-phosphate.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 4.2.1.20).
 9 A0A0B0EAI5 A0A0B0EAI5 P00908 P00908 P06531 P0CN86 P0CN87 P27710 Q92370
Anthranilate phosphoribosyltransferase. [EC: 2.4.2.18]
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).
 1 Q08654
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