The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: Imidazole glycerol phosphate synthase subunit HisH

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Imidazoleglycerol-phosphate synthase activity GO:0000107
Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).
38 Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS)
(28 more)
Carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884
Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.
1 Q603K1 (/ISS)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histidine biosynthetic process GO:0000105
The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
39 Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS) Q48C78 (/ISS)
(29 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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