The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 13: GMP synthase [glutamine-hydrolyzing]
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
|
3 | Q4V7C6 (/IDA) Q57V01 (/IDA) Q57V01 (/IDA) |
|
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
|
2 | Q3THK7 (/ISO) Q3THK7 (/ISO) |
|
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
|
2 | P49915 (/TAS) P49915 (/TAS) |
|
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
|
2 | P49915 (/EXP) P49915 (/EXP) |
|
Deubiquitinase activator activity GO:0035800
Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences.
|
2 | Q8WSN4 (/IDA) Q9VIE7 (/IDA) |
|
GMP synthase activity GO:0003921
Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).
|
1 | Q4V7C6 (/IDA) |
|
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
|
1 | Q4QBY3 (/ISO) |
|
GMP synthase (glutamine-hydrolyzing) activity GO:0003922
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
|
1 | P32073 (/ISS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q4V7C6 (/IDA) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
|
2 | Q3THK7 (/ISO) Q3THK7 (/ISO) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q8WSN4 (/IMP) Q9VIE7 (/IMP) |
|
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
|
2 | P49915 (/TAS) P49915 (/TAS) |
|
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
2 | Q57V01 (/TAS) Q57V01 (/TAS) |
|
Purine ribonucleoside monophosphate biosynthetic process GO:0009168
The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
|
2 | P49915 (/TAS) P49915 (/TAS) |
|
Histone deubiquitination GO:0016578
The modification of histones by removal of ubiquitin groups.
|
2 | Q8WSN4 (/IDA) Q9VIE7 (/IDA) |
|
GMP salvage GO:0032263
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
|
2 | Q57V01 (/IDA) Q57V01 (/IDA) |
|
Regulation of ubiquitin-specific protease activity GO:2000152
Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity.
|
2 | Q8WSN4 (/IDA) Q9VIE7 (/IDA) |
|
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
|
1 | Q4V7C6 (/IDA) |
|
GMP biosynthetic process GO:0006177
The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
|
1 | P32073 (/ISS) |
|
GMP salvage GO:0032263
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
|
1 | Q4QBY3 (/ISO) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q4V7C6 (/IEP) |
|
Positive regulation of smoothened signaling pathway GO:0045880
Any process that activates or increases the frequency, rate or extent of smoothened signaling.
|
1 | Q9VIE7 (/IMP) |
|
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
|
1 | P32073 (/ISS) |
|
Response to L-cysteine GO:1901367
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.
|
1 | Q4V7C6 (/IDA) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A140VJK6 (/IDA) A0A140VJK6 (/IDA) P49915 (/IDA) P49915 (/IDA) Q4V7C6 (/IDA) |
|
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
|
2 | Q8WSN4 (/IDA) Q9VIE7 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q57V01 (/IDA) Q57V01 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q3THK7 (/ISO) Q3THK7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P49915 (/TAS) P49915 (/TAS) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
2 | Q8WSN4 (/IPI) Q9VIE7 (/IPI) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | P32073 (/HDA) |
