The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 218: 2-hydroxy-3-oxopropionate reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
2-hydroxy-3-oxopropionate reductase activity GO:0008679
Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.
|
75 |
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
P77161 (/IDA)
(65 more) |
|
2-hydroxymethylglutarate dehydrogenase activity GO:0043718
Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH.
|
2 | Q0QLF5 (/IDA) Q0QLF5 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
75 |
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
(65 more) |
|
Glyoxylate catabolic process GO:0009436
The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
75 |
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
P77161 (/IMP)
(65 more) |
|
Allantoin assimilation pathway GO:0009442
The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.
|
75 |
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
P77161 (/IEP)
(65 more) |
|
Cofactor catabolic process GO:0051187
The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.
|
2 | Q0QLF5 (/IDA) Q0QLF5 (/IDA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q585Q3 (/IDA) Q585Q3 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
2 | Q585Q3 (/IDA) Q585Q3 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4Q7T9 (/ISO) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
1 | Q4Q7T9 (/ISO) |