The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 214: L-xylulose reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
L-xylulose reductase (NADP+) activity GO:0050038
Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.
|
8 | Q21929 (/IDA) Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) Q91X52 (/IDA) Q91XV4 (/IDA) Q91XV4 (/IDA) Q920N9 (/IDA) Q920P0 (/IDA) |
|
Carbonyl reductase (NADPH) activity GO:0004090
Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
|
3 | P08074 (/IDA) P08074 (/IDA) Q21929 (/IDA) |
|
Carbonyl reductase (NADPH) activity GO:0004090
Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
|
2 | P08074 (/TAS) P08074 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P08074 (/IPI) P08074 (/IPI) |
|
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
|
2 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q7Z4W1 (/IPI) Q7Z4W1 (/IPI) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
2 | P08074 (/IDA) P08074 (/IDA) |
|
L-xylulose reductase (NADP+) activity GO:0050038
Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.
|
2 | Q21929 (/ISS) Q9VWP2 (/ISS) |
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
1 | Q21929 (/IDA) |
|
Oxidoreductase activity, acting on CH-OH group of donors GO:0016614
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
|
1 | Q91X52 (/IDA) |
|
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
|
1 | Q91X52 (/ISO) |
|
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
|
1 | Q9VWP2 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q91X52 (/ISO) |
|
L-xylulose reductase (NADP+) activity GO:0050038
Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.
|
1 | Q91X52 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Xylulose metabolic process GO:0005997
The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
|
7 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) Q91X52 (/IDA) Q91XV4 (/IDA) Q91XV4 (/IDA) Q920N9 (/IDA) Q920P0 (/IDA) |
|
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
7 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) Q91X52 (/IDA) Q91XV4 (/IDA) Q91XV4 (/IDA) Q920N9 (/IDA) Q920P0 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
7 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) Q91X52 (/IDA) Q91XV4 (/IDA) Q91XV4 (/IDA) Q920N9 (/IDA) Q920P0 (/IDA) |
|
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
|
2 | P08074 (/TAS) P08074 (/TAS) |
|
Glucuronate catabolic process to xylulose 5-phosphate GO:0019640
The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.
|
2 | Q7Z4W1 (/TAS) Q7Z4W1 (/TAS) |
|
Protein tetramerization GO:0051262
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
|
2 | P08074 (/IDA) P08074 (/IDA) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
2 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) |
|
Xylulose metabolic process GO:0005997
The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
|
1 | Q91X52 (/ISO) |
|
Xylulose metabolic process GO:0005997
The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
|
1 | Q21929 (/ISS) |
|
Xylulose catabolic process GO:0005998
The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.
|
1 | Q21929 (/IDA) |
|
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
1 | Q91X52 (/ISO) |
|
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
1 | Q21929 (/ISS) |
|
NADP metabolic process GO:0006739
The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
|
1 | Q91X52 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | Q91X52 (/ISO) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | Q21929 (/ISS) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | Q91X52 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
6 | Q1JP75 (/ISS) Q91X52 (/ISS) Q91XV4 (/ISS) Q91XV4 (/ISS) Q920N9 (/ISS) Q920P0 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q7Z4W1 (/HDA) Q7Z4W1 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P08074 (/HDA) P08074 (/HDA) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
2 | Q7Z4W1 (/IDA) Q7Z4W1 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q7Z4W1 (/TAS) Q7Z4W1 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q7Z4W1 (/HDA) Q7Z4W1 (/HDA) |
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
1 | Q91X52 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q21929 (/IDA) |
|
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | Q91X52 (/IDA) |
|
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
|
1 | Q91X52 (/IDA) |
