The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 581: Cystic fibrosis transmembrane conductance regulato...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 35 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
50 P13569 (/ISS) P13569 (/ISS) P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(40 more)
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Intracellularly ATP-gated chloride channel activity GO:0005260
Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
48 P13569 (/ISS) P13569 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(38 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
45 P26361 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS) Q00PJ2 (/ISS)
(35 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P13569 (/IPI) P13569 (/IPI) P26361 (/IPI) P34158 (/IPI)
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
3 P13569 (/IDA) P13569 (/IDA) P26361 (/IDA)
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
3 P13569 (/IDA) P13569 (/IDA) Q1LX78 (/IDA)
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2 P13569 (/TAS) P13569 (/TAS)
Intracellularly ATP-gated chloride channel activity GO:0005260
Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
2 P13569 (/IMP) P13569 (/IMP)
Intracellularly ATP-gated chloride channel activity GO:0005260
Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
2 P13569 (/NAS) P13569 (/NAS)
Intracellularly ATP-gated chloride channel activity GO:0005260
Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
2 P13569 (/TAS) P13569 (/TAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 P13569 (/TAS) P13569 (/TAS)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
2 P13569 (/IDA) P13569 (/IDA)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
2 P13569 (/TAS) P13569 (/TAS)
Chloride channel regulator activity GO:0017081
Modulates the activity of a chloride channel.
2 P13569 (/TAS) P13569 (/TAS)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
2 P13569 (/IDA) P13569 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 P13569 (/IPI) P13569 (/IPI)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
2 P13569 (/IDA) P13569 (/IDA)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
2 P13569 (/IPI) P13569 (/IPI)
Sec61 translocon complex binding GO:0106138
Interacting selectively and non-covalently with a Sec61 translocon complex.
2 P13569 (/IDA) P13569 (/IDA)
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
1 P26361 (/ISO)
Intracellularly ATP-gated chloride channel activity GO:0005260
Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
1 P26361 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q1LX78 (/IDA)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 P26361 (/IMP)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 P26361 (/ISO)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
1 P26361 (/IMP)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 P26361 (/ISO)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
1 P26361 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P26361 (/ISO)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 P26361 (/ISO)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
1 P26361 (/ISO)
Sec61 translocon complex binding GO:0106138
Interacting selectively and non-covalently with a Sec61 translocon complex.
1 P26361 (/ISO)

There are 82 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Transepithelial water transport GO:0035377
The directed movement of water (H2O) from one side of an epithelium to the other.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
48 P13569 (/ISS) P13569 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(38 more)
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Intracellular pH elevation GO:0051454
Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
48 P13569 (/ISS) P13569 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(38 more)
Membrane hyperpolarization GO:0060081
The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
48 P13569 (/ISS) P13569 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(38 more)
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
48 P13569 (/ISS) P13569 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS)
(38 more)
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Cellular response to forskolin GO:1904322
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
45 P26361 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS) Q00PJ2 (/ISS)
(35 more)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
Positive regulation of cyclic nucleotide-gated ion channel activity GO:1902161
Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
3 P13569 (/IDA) P13569 (/IDA) P26361 (/IDA)
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P13569 (/IDA) P13569 (/IDA)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
2 P13569 (/TAS) P13569 (/TAS)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
2 P13569 (/IDA) P13569 (/IDA)
Transepithelial water transport GO:0035377
The directed movement of water (H2O) from one side of an epithelium to the other.
2 P13569 (/IMP) P13569 (/IMP)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
2 P13569 (/IGI) P13569 (/IGI)
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
2 P13569 (/IMP) P13569 (/IMP)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
2 P13569 (/TAS) P13569 (/TAS)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
2 P13569 (/TAS) P13569 (/TAS)
Positive regulation of voltage-gated chloride channel activity GO:1902943
Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.
2 P13569 (/IDA) P13569 (/IDA)
Cellular response to forskolin GO:1904322
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
2 P13569 (/IDA) P13569 (/IDA)
Respiratory burst involved in defense response GO:0002679
A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
1 Q1LX78 (/IMP)
Cholesterol biosynthetic process GO:0006695
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 P26361 (/IMP)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/IGI)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P34158 (/IMP)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/ISO)
Water transport GO:0006833
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P34158 (/IMP)
Water transport GO:0006833
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/ISO)
Vesicle docking involved in exocytosis GO:0006904
The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
1 P26361 (/IMP)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P34158 (/IEP)
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
1 Q1LX78 (/IMP)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P34158 (/IMP)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/ISO)
Iodide transport GO:0015705
The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P34158 (/IMP)
Iodide transport GO:0015705
The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/ISO)
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P26361 (/IMP)
Transepithelial chloride transport GO:0030321
The directed movement of chloride ions from one side of an epithelium to the other.
1 P34158 (/IMP)
Transepithelial chloride transport GO:0030321
The directed movement of chloride ions from one side of an epithelium to the other.
1 P26361 (/ISO)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 P34158 (/IMP)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 P26361 (/ISO)
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
1 Q1LX78 (/IMP)
Cellular response to hormone stimulus GO:0032870
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
1 P34158 (/IEP)
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
1 P34158 (/IMP)
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
1 P26361 (/ISO)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 P34158 (/IEP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P34158 (/IEP)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 P26361 (/ISO)
Transepithelial water transport GO:0035377
The directed movement of water (H2O) from one side of an epithelium to the other.
1 P26361 (/ISO)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 P26361 (/ISO)
Vasodilation GO:0042311
An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
1 P34158 (/IMP)
Vasodilation GO:0042311
An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
1 P26361 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P34158 (/IEP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
1 Q1LX78 (/IMP)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P34158 (/IEP)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P34158 (/IEP)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
1 P26361 (/ISO)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 P26361 (/IMP)
Multicellular organismal water homeostasis GO:0050891
Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
1 P26361 (/ISO)
Intracellular pH elevation GO:0051454
Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 P26361 (/IMP)
Membrane hyperpolarization GO:0060081
The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
1 P26361 (/IMP)
Kupffer's vesicle development GO:0070121
The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
1 Q1LX78 (/IGI)
Kupffer's vesicle development GO:0070121
The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
1 Q1LX78 (/IMP)
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 P26361 (/IDA)
Cellular response to anoxia GO:0071454
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
1 P34158 (/IEP)
Regulation of neutrophil chemotaxis GO:0090022
Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
1 Q1LX78 (/IMP)
Liver regeneration GO:0097421
The regrowth of lost or destroyed liver.
1 P34158 (/IEP)
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
1 P34158 (/IDA)
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
1 P26361 (/ISO)
Positive regulation of cyclic nucleotide-gated ion channel activity GO:1902161
Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
1 P26361 (/ISO)
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
1 P26361 (/ISO)
Positive regulation of voltage-gated chloride channel activity GO:1902943
Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.
1 P26361 (/ISO)
Cellular response to forskolin GO:1904322
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
1 P26361 (/ISO)
Positive regulation of establishment of Sertoli cell barrier GO:1904446
Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.
1 P34158 (/IMP)
Positive regulation of establishment of Sertoli cell barrier GO:1904446
Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.
1 P26361 (/ISO)
Negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
1 P34158 (/IMP)
Negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
1 P26361 (/ISO)
Negative regulation of type B pancreatic cell development GO:2000077
Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.
1 P34158 (/IMP)
Negative regulation of type B pancreatic cell development GO:2000077
Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.
1 P26361 (/ISO)

There are 50 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
48 P26361 (/ISS) P26362 (/ISS) P26363 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS)
(38 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
45 P13569 (/ISS) P13569 (/ISS) P26361 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS)
(35 more)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
45 P26361 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS) Q00PJ2 (/ISS)
(35 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
45 P26361 (/ISS) P34158 (/ISS) P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS) Q00PJ2 (/ISS)
(35 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
43 P35071 (/ISS) Q00552 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00553 (/ISS) Q00554 (/ISS) Q00555 (/ISS) Q00PJ2 (/ISS) Q07DV2 (/ISS) Q07DW5 (/ISS)
(33 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
5 P13569 (/IDA) P13569 (/IDA) P26361 (/IDA) P34158 (/IDA) Q1LX78 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P13569 (/IDA) P13569 (/IDA) P34158 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P13569 (/IDA) P13569 (/IDA) P26361 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P13569 (/IDA) P13569 (/IDA) P26361 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P13569 (/IMP) P13569 (/IMP) P26361 (/IMP)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P13569 (/IDA) P13569 (/IDA) Q1LX78 (/IDA)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
2 P13569 (/TAS) P13569 (/TAS)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2 P13569 (/IDA) P13569 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 P13569 (/IDA) P13569 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 P13569 (/TAS) P13569 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P13569 (/TAS) P13569 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P13569 (/TAS) P13569 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P13569 (/IDA) P13569 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P13569 (/IDA) P13569 (/IDA)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
2 P13569 (/TAS) P13569 (/TAS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 P13569 (/IMP) P13569 (/IMP)
Golgi-associated vesicle membrane GO:0030660
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
2 P13569 (/TAS) P13569 (/TAS)
Clathrin-coated vesicle membrane GO:0030665
The lipid bilayer surrounding a clathrin-coated vesicle.
2 P13569 (/TAS) P13569 (/TAS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 P13569 (/IDA) P13569 (/IDA)
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
2 P13569 (/IDA) P13569 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P34158 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P26361 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P26361 (/ISO)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 P26361 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 P26361 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P26361 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P26361 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P26361 (/ISO)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
1 P34158 (/IDA)
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
1 P26361 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P26361 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P26361 (/ISO)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 P34158 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 P26361 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 P26361 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P34158 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P26361 (/ISO)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
1 P34158 (/IDA)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
1 P26361 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P26361 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P34158 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P26361 (/ISO)
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
1 P26361 (/ISO)
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